Compound Q&A

How is N-(4-Nitrophenyl)acetamide (CAS: 104-04-1) typically synthesized?

Answer

N-(4-Nitrophenyl)acetamide
N-(4-Nitrophenyl)acetamide is typically synthesized by the acetylation of 4-nitrophenol using acetic anhydride in the presence of a catalyst such as pyridine. The reaction is carried out at room temperature, and the yield is generally around 85-90%. The product is then purified by recrystallization.

About

CAS No 104-04-1
English Name N-(4-Nitrophenyl)acetamide
Molecular Formula C8H8N2O3
Molecular Weight 180.16 g/mol
SMILES CC(=O)NC1=CC=C(C=C1)[N+](=O)[O-]
InChIKey NQRLPDFELNCFHW-UHFFFAOYSA-N
Last Updated: 2025-09-26 00:09

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