4-Amino-3-(trifluoromethyl)benzoic acid(CAS: 400-76-0)

4-Amino-3-(trifluoromethyl)benzoic acid is a white crystalline solid with a molecular weight of approximately 263.08 g/mol. It has low water solubility (less than 0.1 g/L at 20°C) but is soluble in organic solvents like DMSO and acetonitrile. This compound is known for its low reactivity and stability under normal conditions.

4-Amino-3-(trifluoromethyl)benzoic acid is typically synthesized through a multi-step process starting from benzoic acid. The key steps include trifluoromethylation of benzoic acid followed by reduction to form the amino group. The synthesis requires mild conditions and can be catalyzed by various reagents to achieve high selectivity and yield.

4-Amino-3-(trifluoromethyl)benzoic acid (CAS: 400-76-0) is used in the pharmaceutical industry for synthesizing certain drug intermediates. It is also utilized in the polymer industry as a monomer or additive, and in the semiconductor industry for its electronic properties. Additionally, it is explored in sensor technology for its specific chemical reactivity.

When handling 4-Amino-3-(trifluoromethyl)benzoic acid (CAS: 400-76-0), it is important to use personal protective equipment (PPE) such as gloves and safety goggles. This compound should be stored in a cool, dry place away from direct sunlight and heat sources. In case of a spill, it should be absorbed using appropriate materials and the area should be cleaned with water. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.