(4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one(CAS: 33457-62-4)

(4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one is a colorless solid with a molecular weight of 246.26 g/mol. It has a melting point of 78-80°C and is soluble in common organic solvents like acetone and dichloromethane. It is known for its high reactivity, especially towards nucleophiles and electrophiles, making it useful in various synthetic transformations.

(4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one can be synthesized via Wittig reaction of a phenylphosphonate with 1,7-diphenyl-1,3-heptadiene. Alternatively, it can be prepared from a Grignard reagent derived from phenylmagnesium bromide and 1,3-heptadiene. The yield and selectivity are generally good, and appropriate solvents and temperatures are crucial for the reaction to proceed smoothly.

(4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one is widely used in the pharmaceutical industry for the synthesis of various medicinal compounds. It is also utilized in the polymer industry to modify polymer properties. Its ability to act as a precursor in semiconductor and sensor technology makes it valuable in these sectors as well.

When handling (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to minimize inhalation risks. Spills should be cleaned up with appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.