[3-(Acryloylamino)phenyl]boronic acid(CAS: 99349-68-5)

[3-(Acryloylamino)phenyl]boronic acid (CAS: 99349-68-5) is a white crystalline solid. It has a molecular weight of approximately 230.21 g/mol. This compound is soluble in organic solvents like DMF, DMSO, and THF but poorly soluble in water. It exhibits excellent reactivity with aldehydes and ketones, making it a valuable reagent in organic synthesis. It also shows good stability under acidic conditions but can be sensitive to strong bases.

[3-(Acryloylamino)phenyl]boronic acid (CAS: 99349-68-5) is synthesized by the condensation of 3-aminophenol with acryloyl chloride in the presence of a base such as triethylamine. This reaction typically yields a 90% pure product with excellent selectivity. The synthetic route is straightforward and can be performed in one step, making it a viable method for industrial-scale production.

[3-(Acryloylamino)phenyl]boronic acid (CAS: 99349-68-5) finds application in various industries including pharmaceuticals, where it is used as a chelating agent and for the synthesis of drug intermediates. It is also utilized in the polymer industry for functionalizing polymers and in the electronics sector for semiconductor applications. Additionally, it is employed in the development of biosensors for its ability to bind specifically with certain molecules.

When handling [3-(Acryloylamino)phenyl]boronic acid (CAS: 99349-68-5), it is essential to wear appropriate protective equipment such as gloves, goggles, and lab coat to prevent skin and eye contact. This compound should be stored in a well-ventilated area away from direct sunlight and moisture. In case of a spill, it should be carefully cleaned up using absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.