3,5-Dimethoxybenzoic acid(CAS: 1132-21-4)

3,5-Dimethoxybenzoic acid (CAS: 1132-21-4) is a crystalline solid with a molecular weight of approximately 188.16 g/mol. It has a melting point of 225-227°C and a pKa of about 4.1. The acid is moderately soluble in water and ethanol, but less soluble in other organic solvents. It is chemically reactive, especially towards nucleophiles and bases.

3,5-Dimethoxybenzoic acid is typically synthesized by the methylation of 3,5-dihydroxybenzoic acid using a methylating agent like methyl iodide in the presence of a base such as sodium hydroxide. The reaction is carried out in an aprotic solvent like dimethylformamide (DMF) to achieve a high yield and selectivity.

3,5-Dimethoxybenzoic acid (CAS: 1132-21-4) is used in various industries, including pharmaceuticals for the synthesis of certain drugs, polymers as a monomer or intermediate, and in the production of sensors and semiconductors due to its unique chemical properties.

When handling 3,5-Dimethoxybenzoic acid (CAS: 1132-21-4), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be performed in a well-ventilated area or under a fume hood. Spills should be cleaned up immediately using appropriate absorbent materials, and proper disposal methods should be followed according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.