[Pyr1]-Apelin-13(CAS: 217082-60-5)

[Pyr1]-Apelin-13 is a peptide with a molecular weight of approximately 721.56 g/mol. It is somewhat soluble in water and has a crystalline form. The compound is stable under normal conditions but reacts with bases to form salts. It is not flammable but should be handled with care due to potential irritancy.

[Pyr1]-Apelin-13 is synthesized via solid-phase peptide synthesis (SPPS) using Fmoc chemistry. The synthesis involves the stepwise addition of amino acids to a growing peptide chain on a solid support. Commonly used catalysts include HATU or DCC. The final product is cleaved from the solid support using strong acids like trifluoroacetic acid (TFA).

[Pyr1]-Apelin-13 is primarily used in the pharmaceutical industry for research and development of potential therapeutic agents. It is also used in biological and medical research to study the apelin receptor. Limited applications exist in polymer and sensor industries due to its specific biological activity.

When handling [Pyr1]-Apelin-13, wear appropriate personal protective equipment (PPE) such as gloves and goggles. Store the compound in a cool, dry place away from direct sunlight. Use a fume hood during synthesis and handling to minimize exposure. In case of spill, immediately follow the safety data sheet (SDS) guidelines for disposal and clean-up. Seek medical advice if exposed to the compound. Ensure proper ventilation and disposal methods are in place to prevent environmental contamination.