2-Methyl-2-propanyl 1-oxo-7-azaspiro[3.5]nonane-7-carboxylate(CAS: 849203-60-7)

2-Methyl-2-propanyl 1-oxo-7-azaspiro[3.5]nonane-7-carboxylate is a white crystalline powder. Its molecular weight is approximately 272.4 g/mol. It is slightly soluble in water but soluble in organic solvents like dichloromethane and acetone. The compound is moderately reactive, displaying some acid-labile ester functionality. It is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight.

2-Methyl-2-proanyl 1-oxo-7-azaspiro[3.5]nonane-7-carboxylate is typically synthesized via a multi-step process involving the condensation of a protected azaspiro compound with a carboxylic acid derivative. The reaction is catalyzed by a Lewis acid like boron trifluoride or a mild acid such as acetic acid. The method ensures high yield and good selectivity, making it suitable for industrial-scale production.

2-Methyl-2-proanyl 1-oxo-7-azaspiro[3.5]nonane-7-carboxylate finds application in the pharmaceutical industry for synthesizing complex natural products and drug intermediates. It is also used in the polymer industry for the development of functional polymers. In addition, it is explored for use in sensors and semiconductor manufacturing due to its unique chemical properties.

When handling 2-Methyl-2-proanyl 1-oxo-7-azaspiro[3.5]nonane-7-carboxylate, it is crucial to use appropriate personal protective equipment (PPE) such as gloves and safety goggles. The compound should be stored in a cool, dry place away from direct sunlight and heat sources. In case of a spill, it should be handled in a well-ventilated area, and the spill should be cleaned up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.