3-Fluoropyridine

Basic Information

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CAS Number

372-47-4

Molecular Formula

C5H4FN

Molecular Weight

97.09 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

251-254°C (dec.)

Boiling Point

106°C

Refractive Index

n20/D 1.472(lit.)

SMILES

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C1=CC(=CN=C1)F

InChI

InChI=1S/C5H4FN/c6-5-2-1-3-7-4-5/h1-4H

InChIKey

CELKOWQJPVJKIL-UHFFFAOYSA-N

LogP

1.2207000000000001

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

Safety Information

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GHS Hazard Pictograms

H225

H315

H319

H335

Hazard Statement

H225 Highly Flammable liquid and vapor
Flammable liquids

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 3 Class 3

Synonyms & References

English

DTXSID10190688
F0207
EINECS 206-755-4
NSC-5078
SB52271
AC-7017
BCP23075
CHEMBL1162361
AP9KGY2VWZ
3-Fluoropyridine
NS00041742
MFCD00006374
Q-103374
FT-0615750
Pyridine, 3-fluoro-
3-Fluoro-pyridinium
UNII-AP9KGY2VWZ
EN300-21360
F0001-1072
NSC5078
AKOS005145578
AM20051123
NSC 5078
CCRIS 1717
3-fluropyridine
3-fluoro-pyridine
BP-11394
3-Fluoropyridine, 99%
CS-W011338
372-47-4
InChI=1/C5H4FN/c6-5-2-1-3-7-4-5/h1-4

MDL Number

MFCD00006374

FAQ

What is 3-Fluoropyridine (CAS: 372-47-4)?

3-Fluoropyridine (CAS: 372-47-4) is a heterocyclic aromatic organic compound with the chemical formula C5H4FN. It is a colorless solid at room temperature, known for its strong odor and solubility in organic solvents. This compound is characterized by a pyridine ring substituted with a fluorine atom at the 3-position, making it a key intermediate in various chemical applications. Its reactivity and functional group make it useful in synthetic chemistry.

What are the main uses of 3-Fluoropyridine (CAS: 372-47-4)?

3-Fluoropyridine (CAS: 372-47-4) is widely used in pharmaceuticals as a building block for drug development, including antidepressants and antifungal agents. It also serves industrial purposes in the synthesis of agrochemicals, dyes, and materials. In research, it is employed as a versatile starting material for creating fluorinated derivatives. Its applications are supported by its chemical stability and reactivity, making it valuable in multiple sectors.

Is 3-Fluoropyridine (CAS: 372-47-4) safe?

3-Fluoropyridine (CAS: 372-47-4) requires careful handling due to potential toxicity. It may cause skin and eye irritation, and inhalation can be harmful. Safety measures include using protective gloves, goggles, and ventilation. Exposure limits are regulated by OSHA and EPA guidelines. Always follow proper safety protocols when working with this compound to minimize risks.

How should 3-Fluoropyridine (CAS: 372-47-4) be stored?

3-Fluoropyridine (CAS: 372-47-4) should be stored in a cool, dry, and dark place, ideally at 25°C. It requires low humidity conditions and should be kept in a sealed, airtight container to prevent moisture and air exposure. Avoid direct light and store away from incompatible materials. Proper storage ensures stability and safety, as recommended by chemical handling standards.