N-[4-(4-Fluorophenyl)-5-(hydroxymethyl)-6-isopropyl-2-pyrimidinyl]-N-methylmethanesulfonamide | CAS No. 147118-36-3

N-[4-(4-Fluorophenyl)-5-(hydroxymethyl)-6-isopropyl-2-pyrimidinyl]-N-methylmethanesulfonamide

Basic Information

CAS Number

147118-36-3

Molecular Formula

C16H20FN3O3S

Molecular Weight

353.42 g/mol

AD

Basic Physical Properties

Boiling Point

538.3°C at 760 mmHg

CC(C)C1=NC(=NC(=C1CO)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C

InChI

InChI=1S/C16H20FN3O3S/c1-10(2)14-13(9-21)15(11-5-7-12(17)8-6-11)19-16(18-14)20(3)24(4,22)23/h5-8,10,21H,9H2,1-4H3

InChIKey

MSDYDUNHTAYBHV-UHFFFAOYSA-N

LogP

2.2942

Topological Polar Surface Area

83.39000000000001 Ų

Hydrogen Bond Donor/Acceptor

1 / 6

Complexity

503

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral
H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • SB58016
  • AC-447
  • SCHEMBL2690
  • DTXSID90431324
  • 4-(4-Fluorophenyl)-6-isopropyl-2-(N-methyl-N-methanesulfonylamino) pyrimidin-5-methanol
  • [4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulphonylamino)pyrimidin-5-yl]methanol
  • N-[4-(4-fluorophenyl)-5-hydroxymethyl-6-isopropyl-pyrimidin-2-yl]-N-methyl-methanesulfonamide
  • SY046716
  • 147118-36-3
  • N-(4-(4-fluorophenyl)-5-(hydroxymethyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide;4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-N-methylsufonyl)amino]pyrimidine-5-yl-methanol
  • N-[4-(4-Fluorophenyl)-5-hydroxymethyl-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide
  • [4-(4-fluorophenyl0-6-isopropyl-2-(N-methyl-N-methylsulfonyl-amino)pyrimidin-5-yl]methano
  • 4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(N-METHYL-N-METHYLSULFONYLAMINO)PYRIMIDINE-5-METHANOL
  • 4-(4-Fluorophenyl)-5-(hydroxymethyl)-6-isopropyl-2-(N-methylmethanesulfonylamino)pyrimidine
  • BCP26429
  • METHANESULFONAMIDE, N-[4-(4-FLUOROPHENYL)-5-(HYDROXYMETHYL)-6-(1-METHYLETHYL)-2-PYRIMIDINYL]-N-METHYL-
  • EN300-6477466
  • 4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-N-methylsufonyl)amino]pyrimidine-5-yl-methanol
  • N-[4-(4-FLUOROPHENYL)-5-(HYDROXYMETHYL)-6-(PROPAN-2-YL)PYRIMIDIN-2-YL]-N-METHYLMETHANESULFONAMIDE
  • [4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]methanol
  • MFCD08063917
  • N-[4-(4-fluorophenyl)-5-(hydroxymethyl)-6-propan-2-ylpyrimidin-2-yl]-N-methylmethanesulfonamide
  • s10387
  • FT-0643399
  • 4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine-5-methanol
  • AKOS015897401
  • N-(4-(4-fluorophenyl)-5-(hydroxymethyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide
  • A23364
  • 4-(4-fluorophenyl)-6-isopropyl-2-[(N-methyl-N-methylsulfonyl) amino] pyrimidine-5-yl-methanol
  • J-513515
  • DS-11314

MDL Number

MFCD08063917

Customs Code

2935009090

FAQ

What is N-[4-(4-Fluorophenyl)-5-(hydroxymethyl)-6-isopropyl-2-pyrimidinyl]-N-methylmethanesulfonamide (CAS: 147118-36-3)?

N-[4-(4-Fluorophenyl)-5-(hydroxymethyl)-6-isopropyl-2-pyrimidinyl]-N-methylmethanesulfonamide (CAS: 147118-36-3) is a chemical compound with a complex structure that includes a pyrimidine ring substituted with various functional groups. It is typically used as an intermediate in the synthesis of pharmaceutical compounds and is known for its stability under normal conditions. The compound exhibits moderate solubility in polar solvents and is commonly encountered in research and development settings.

What are the main uses of N-[4-(4-Fluorophenyl)-5-(hydroxymethyl)-6-isopropyl-2-pyrimidinyl]-N-methylmethanesulfonamide (CAS: 147118-36-3)?

N-[4-(4-Fluorophenyl)-5-(hydroxymethyl)-6-isopropyl-2-pyrimidinyl]-N-methylmethanesulfonamide (CAS: 147118-36-3) is primarily used as an intermediate in the production of pharmaceuticals, particularly in the development of drugs targeting metabolic disorders. It also finds application in chemical research and can be used in the synthesis of other complex organic molecules. Its utility lies in its reactivity and structural versatility.

Is N-[4-(4-Fluorophenyl)-5-(hydroxymethyl)-6-isopropyl-2-pyrimidinyl]-N-methylmethanesulfonamide (CAS: 147118-36-3) safe?

N-[4-(4-Fluorophenyl)-5-(hydroxymethyl)-6-isopropyl-2-pyrimidinyl]-N-methylmethanesulfonamide (CAS: 147118-36-3) is generally considered safe when handled properly. However, as a chemical intermediate, it may require caution due to potential irritant properties. It is advisable to use appropriate personal protective equipment (PPE) and follow standard laboratory safety protocols to minimize exposure and ensure safe handling.

How should N-[4-(4-Fluorophenyl)-5-(hydroxymethyl)-6-isopropyl-2-pyrimidinyl]-N-methylmethanesulfonamide (CAS: 147118-36-3) be stored?

N-[4-(4-Fluorophenyl)-5-(hydroxymethyl)-6-isopropyl-2-pyrimidinyl]-N-methylmethanesulfonamide (CAS: 147118-36-3) should be stored in a cool, dry, and well-ventilated area, away from light. It is best kept in a sealed container at a temperature below 25°C to maintain stability. Avoid exposure to moisture and ensure proper storage to prevent degradation or contamination.

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