4-Nitro-1H-indole(CAS: 4769-97-5)

4-Nitro-1H-indole (CAS: 4769-97-5) is a yellow crystalline solid with a molecular weight of 177.08 g/mol. It is slightly soluble in water but soluble in organic solvents like ethanol. It is moderately reactive and can undergo nitration and reduction reactions. The compound is stable under normal conditions but should be stored away from heat and reducing agents.

4-Nitro-1H-indole (CAS: 4769-97-5) is typically synthesized by the nitration of indole. A mixture of indole and sulfuric acid is treated with a nitric acid solution. The process is carried out in a water bath to maintain the temperature and ensure a high yield. The product is then purified by recrystallization.

4-Nitro-1H-indole (CAS: 4769-97-5) is used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the production of dyes and pigments. Additionally, it is used in the development of sensors and as a precursor in the synthesis of semiconductors.

When handling 4-Nitro-1H-indole (CAS: 4769-97-5), it is crucial to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials, and the area should be well-ventilated. Always consult the Safety Data Sheet (SDS) for detailed handling instructions.