Cefamandole nafate(CAS: 42540-40-9)

Cefamandole nafate (CAS: 42540-40-9) is a crystalline compound with a molecular weight of approximately 482.5 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol. Chemically, it is relatively stable but can react with strong acids or bases. It is used in pharmaceutical formulations for its antimicrobial properties.

Cefamandole nafate (CAS: 42540-40-9) is synthesized through a multi-step process involving the acylation of a specific intermediate. The synthesis typically requires strong acids as catalysts and involves selective reactions to ensure the formation of the desired product. The overall yield is around 80%, with high selectivity towards the desired product.

Cefamandole nafate (CAS: 42540-40-9) is primarily used in the pharmaceutical industry for the production of antibiotics. It is incorporated into various antimicrobial formulations to treat bacterial infections. While not commonly used in other industries, it may have applications in research and development for new drug compounds.

When handling Cefamandole nafate (CAS: 42540-40-9), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Operations should be conducted in a well-ventilated area or fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbents, and the area should be thoroughly washed with water. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.