Ethyl 1,3-benzothiazol-2-ylacetate(CAS: 29182-42-1)

Ethyl 1,3-benzothiazol-2-ylacetate (CAS: 29182-42-1) is a crystalline compound with a molecular weight of approximately 222.24 g/mol. It is soluble in organic solvents like ethanol and acetone but has limited water solubility. The compound exhibits moderate reactivity towards nucleophiles and electrophiles, suitable for various synthetic transformations.

Ethyl 1,3-benzothiazol-2-ylacetate is typically synthesized via the acylation of 1,3-benzothiazol-2-amine with ethyl acetoacetate. This reaction is catalyzed by a Lewis acid like aluminum trichloride and proceeds with good yield under mild conditions. The method involves careful temperature control to ensure high selectivity and purity.

Ethyl 1,3-benzothiazol-2-ylacetate is used in various industries, including pharmaceuticals, where it functions as a precursor for synthesizing bioactive compounds. It is also utilized in organic synthesis and the production of sensors and semiconductors due to its unique chemical properties.

When handling Ethyl 1,3-benzothiazol-2-ylacetate (CAS: 29182-42-1), it is essential to use appropriate personal protective equipment (PPE), including gloves and safety goggles. The compound should be stored in a cool, dry place, away from direct sunlight and heat sources. In case of a spill, handle it carefully using appropriate cleanup procedures and consult the Safety Data Sheet (SDS) for detailed instructions.