2-Chloro-4-ethoxypyrimidine(CAS: 83774-09-8)

2-Chloro-4-ethoxypyrimidine (CAS: 83774-09-8) is a solid crystalline compound with a molecular weight of approximately 185.01 g/mol. It has a high solubility in organic solvents like dimethylformamide (DMF) and methanol. Chemically, it is reactive, particularly towards nucleophiles and can undergo substitution reactions. It is insoluble in water.

2-Chloro-4-ethoxypyrimidine can be synthesized via the reaction of 4-ethoxypyrimidine with thionyl chloride in the presence of a solvent such as toluene. The process typically involves the formation of an intermediate which then undergoes further substitution to yield the target compound. The reaction is usually carried out at room temperature with good yield and selectivity.

2-Chloro-4-ethoxypyrimidine (CAS: 83774-09-8) is used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the polymer industry for the development of specific polymers and in the semiconductor industry for sensor applications. Its reactivity makes it valuable in these areas.

When handling 2-Chloro-4-ethoxypyrimidine (CAS: 83774-09-8), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be handled using appropriate spill kits, and the material safety data sheet (MSDS) should be consulted for detailed information on safe handling and disposal.