How is 2-Chloro-4-ethoxypyrimidine (CAS: 83774-09-8) typically synthesized?

2-Chloro-4-ethoxypyrimidine can be synthesized via the reaction of 4-ethoxypyrimidine with thionyl chloride in the presence of a solvent such as toluene. The process typically involves the formation of an intermediate which then undergoes further substitution to yield the target compound. The reaction is usually carried out at room temperature with good yield and selectivity.