Noroxymorphone(CAS: 33522-95-1)

Noroxymorphone is a white or off-white crystalline powder with a molecular weight of 344.39 g/mol. It is slightly soluble in water and alcohol. The compound is stable under normal storage conditions but can degrade upon prolonged exposure to heat and light. It is a potent opioid analgesic with a high affinity for the μ-opioid receptor.

Noroxymorphone is synthesized through a series of chemical reactions, including the reduction of oxymorphone to noroxymorphone. Common methods involve the use of hydrogenation catalysts such as palladium on carbon. The reaction typically yields a high purity product, though careful monitoring of reaction conditions is necessary to achieve the desired selectivity and yield.

Noroxymorphone is primarily used in the pharmaceutical industry due to its analgesic properties. It is also of interest in academic research for studying opioid receptor function. While not commonly used in other industries like polymers or semiconductors, its unique chemical properties make it a subject of study in sensor technology.

When handling Noroxymorphone, appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up using appropriate absorbents and disposed of according to local regulations. Always consult the Material Safety Data Sheet (MSDS/SDS) for detailed information on handling and storage.