Sisomicin | CAS No. 32385-11-8

Sisomicin

Basic Information

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CAS Number

32385-11-8

Molecular Formula

C19H37N5O7

Molecular Weight

447.5 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

80-93°C

Boiling Point

556.56°C (rough estimate)

Flash Point

363°C

Refractive Index

1.7600 (estimate)

SMILES

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CC1(COC(C(C1NC)O)OC2C(CC(C(C2O)OC3C(CC=C(O3)CN)N)N)N)O

InChI

InChI=1S/C19H37N5O7/c1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17/h3,9-18,24-27H,4-7,20-23H2,1-2H3/t9-,10+,11-,12+,13-,14-,15+,16-,17-,18-,19+/m1/s1

InChIKey

URWAJWIAIPFPJE-YFMIWBNJSA-N

LogP

-0.23140

Complexity

643

Synonyms & References

English

BRN 1357913
SISOMICIN [WHO-DD]
O-3-Deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-4)-O-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-glycero-hex-4-enopyranosyl-(1-6))-2-deoxy-L-streptamine
Sisomicinum
O-2,6-Diamino-2,3,4,6-tetradeoxy-alpha-D-glycero-hex-4-enopyranosyl-(1-4)-O-(3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6)-2-deoxy-D-streptamine
O-3-DEOXY-4-C-METHYL-3-(METHYLAMINO)-.BETA-L-ARABINOPYRANOSYL-(1->4)-O-(2,6-DIAMINO-2,3,4,6-TETRADEOXY-.ALPHA.-D-GLYCERO-HEX-4-ENOPYRANOSYL-(1->6))-2-DEOXY-L-STREPTAMINE
EINECS 251-018-2
Sisomicine
Sisomicin [USAN:INN:BAN]
SISOMICIN [MI]
Sisomicine [INN-French]
Antibiotic 6640
CHEBI:9169
SISO
SCHEMBL49395
URWAJWIAIPFPJE-YFMIWBNJSA-N
(2S-CIS)-4-O-(3-AMINO-6-(AMINOMETHYL)-3,4-DIHYDRO-2H-PYRAN-2-YL)-2-DEOXY-6-O-(3-DEOXY-4-C-METHYL-3-(METHYLAMINO)-.BETA.-L-ARABINOPYRANOSYL)-D-STREPTAMINE
O-2,6-Diamino-2,3,4,6-tetradeoxy-alpha-D-glycero-hex-4-enopyranosyl-(1-4)-O-(3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6))-2-deoxy-D-streptamine
Sisomicin (USAN/INN)
Sisomicinum [INN-Latin]
Sisomicina [INN-Spanish]
SiS
D-Streptamine, O-3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6)-O-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-glycero-hex-4-enopyranosyl-(1-4))-2-deoxy-
Sch 13475
GTPL10858
SISOMICIN [INN]
(2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy]-2-hydroxy-cyclohexoxy]-5-methyl-4-(methylamino)tetrahydropyran-3,5-diol
C00494
D02544
2-DEOXY-4-O-(3-DEOXY-4-C-METHYL-3-(METHYLAMINO)-.BETA.-L-ARABINOPYRANOSYL)-6-O-(2,6-DIAMINO-2,3,4,6-TETRADEOXY-.ALPHA.-D-GLYCERO-HEX-4-ENOPYRANOSYL)-L-STREPTAMINE
Sch13475

MDL Number

MFCD00059734

FAQ

What is Sisomicin (CAS: 32385-11-8)?

Sisomicin (CAS: 32385-11-8) is an aminoglycoside antibiotic with potent antibacterial activity. It is primarily used in veterinary medicine to treat severe infections caused by gram-negative bacteria.

What are the main uses of Sisomicin (CAS: 32385-11-8)?

Sisomicin (CAS: 32385-11-8) is mainly used in veterinary medicine for treating severe infections caused by gram-negative bacteria. It is also used in limited human applications, particularly in ophthalmology for the treatment of certain bacterial eye infections.

Is Sisomicin (CAS: 32385-11-8) safe?

Sisomicin (CAS: 32385-11-8) is generally considered safe when used under medical supervision. However, it can cause nephrotoxicity and ototoxicity, so it is important to follow strict dosing guidelines and monitor for adverse effects.

How should Sisomicin (CAS: 32385-11-8) be stored?

Sisomicin (CAS: 32385-11-8) should be stored at a temperature between 15-25°C (59-77°F), protected from light and moisture. It should be kept in tightly sealed containers to prevent degradation. Avoid exposure to direct sunlight and high humidity.