tert-Butyl (5-bromothiophen-2-yl)carbamate(CAS: 943321-89-9)

Tert-Butyl (5-bromothiophen-2-yl)carbamate (CAS: 943321-89-9) is a white to off-white crystalline solid with a molecular weight of approximately 314.03 g/mol. It has a low solubility in water but is more soluble in organic solvents like methanol and dichloromethane. This compound is known for its high reactivity, particularly towards nucleophiles, and is often used in organic synthesis due to its bromine-containing thiophene moiety.

Tert-Butyl (5-bromothiophen-2-yl)carbamate (CAS: 943321-89-9) can be synthesized via a multi-step process. A common method involves the reaction of tert-butyl carbamate with 2-bromothiophene under basic conditions. The reaction typically proceeds with a yield of around 75-80% and requires careful control of reaction conditions to ensure selectivity and high purity of the product.

Tert-Butyl (5-bromothiophen-2-yl)carbamate (CAS: 943321-89-9) is primarily used in pharmaceutical and chemical industries due to its reactivity and functionality. It serves as a key intermediate in the synthesis of various organic compounds, particularly those involving thiophene derivatives, which are important in pharmaceuticals, polymers, and sensors.

When handling tert-Butyl (5-bromothiophen-2-yl)carbamate (CAS: 943321-89-9), it is crucial to use appropriate personal protective equipment (PPE) such as gloves and safety goggles. This compound should be handled in a fume hood due to its potential volatility and reactivity. In case of a spill, it is recommended to clean up using appropriate absorbent materials and ensure proper disposal. Always refer to the safety data sheet (SDS) for comprehensive safety information and guidelines.