Sodium 4-fluorobenzenesulfinate(CAS: 824-80-6)

Sodium 4-fluorobenzenesulfinate (CAS: 824-80-6) is a crystalline compound with a molecular weight of approximately 214.14 g/mol. It has a low solubility in water (0.19 g/100 mL at 20°C) and is soluble in organic solvents like ethanol and acetone. The compound is known for its moderate reactivity with strong bases and is generally stable under normal conditions but may react with acidic substances. It is often used in organic synthesis and as an intermediate in the production of pharmaceuticals and other chemical products.

Sodium 4-fluorobenzenesulfinate (CAS: 824-80-6) is typically synthesized by the reaction of sodium sulfinate with 4-fluorobenzenesulfonyl chloride. The synthesis involves the use of a phase-transfer catalyst to improve the reaction yield. The process requires careful control of temperature and reagent proportions to achieve high selectivity and yield, typically resulting in a yield of 70-80%. The product is usually purified by recrystallization or column chromatography.

Sodium 4-fluorobenzenesulfinate (CAS: 824-80-6) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It is also utilized in the polymer industry for the production of specialized polymers and in the semiconductor industry for the fabrication of electronic components. Additionally, it finds applications in the sensor industry due to its reactivity and stability.

When handling Sodium 4-fluorobenzenesulfinate (CAS: 824-80-6), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat to avoid skin and eye contact. The compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risks. In case of spills, they should be carefully cleaned up using appropriate absorbents, and the area should be flushed with water. Always consult the Safety Data Sheet (SDS) for specific handling and storage guidelines to ensure safe laboratory practices.