Warfarin EP Impurity B (4-Hydroxy Coumarin)(CAS: 1076-38-6)

Warfarin EP Impurity B, also known as 4-Hydroxy Coumarin, is a chemical compound with the formula C8H6O2. It is a white crystalline powder, highly soluble in ethanol and water, and has a melting point of approximately 110°C. As a derivative of coumarin, it serves as an impurity in the pharmaceutical compound warfarin, which is an anticoagulant used in medicine.

Warfarin EP Impurity B is primarily encountered in pharmaceutical quality control as an impurity in warfarin production. It is also used in research for studying anticoagulant mechanisms and as a reference standard. Industrially, coumarin derivatives like this compound may serve as precursors in organic synthesis or flavoring agents, though its specific applications are limited to controlled environments.

Warfarin EP Impurity B is generally considered safe when handled according to standard safety protocols. However, it may cause skin irritation or respiratory issues upon exposure. Safety data sheets (SDS) recommend using protective gloves, goggles, and ensuring adequate ventilation. It is classified as a low-toxicity compound but should be treated with caution in industrial and research settings.

Warfarin EP Impurity B should be stored in a cool, dry place, away from direct light, and in airtight containers to prevent moisture absorption. It is stable under normal storage conditions but may degrade if exposed to high temperatures or humidity. Proper storage ensures its integrity and minimizes potential safety risks during handling.