Disodium 2'-deoxy-5'-O-phosphonatoinosine(CAS: 14999-52-1)

Disodium 2'-deoxy-5'-O-phosphonatoinosine is a white crystalline solid with a molecular weight of approximately 427.21 g/mol. It is poorly soluble in water and ethanol. The compound is reactive towards nucleophilic substitution and can form ester bonds under appropriate conditions. It is stable under anhydrous conditions but should be protected from moisture and light.

Disodium 2'-deoxy-5'-O-phosphonatoinosine is typically synthesized through the condensation of 2'-deoxy-5'-phosphononucleoside with sodium hydroxide, followed by the addition of a deoxyribose moiety. This process occurs under acidic conditions and the reaction is catalyzed by a suitable organic acid. The yield is generally around 85% with high selectivity towards the desired product.

Disodium 2'-deoxy-5'-O-phosphonatoinosine is primarily used in the pharmaceutical industry for the development of antiviral drugs. It is also applied in the polymer industry for synthesizing novel polymeric materials with specific properties. Additionally, it is used in the production of sensors and semiconductors for their unique biological recognition capabilities.

When handling Disodium 2'-deoxy-5'-O-phosphonatoinosine, it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. Spills should be promptly cleaned up using the appropriate spill kit. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and disposal procedures.