4-(3-Oxo-4-morpholinyl)benzoic acid(CAS: 720720-60-5)

4-(3-Oxo-4-morpholinyl)benzoic acid (CAS: 720720-60-5) is a crystalline solid with a molecular weight of approximately 237.3 g/mol. It has a limited water solubility and is slightly soluble in common organic solvents like ethanol and acetone. The compound is known for its low reactivity under typical laboratory conditions but can undergo ring-opening reactions under strong basic conditions. It is stable under neutral and acidic conditions.

4-(3-Oxo-4-morpholinyl)benzoic acid is typically synthesized through the condensation of 4-morpholinobenzoic acid with acetic anhydride. This reaction is carried out under mild heating conditions, and the product is isolated by recrystallization from water. The yield is generally around 85%, and the reaction is catalyzed by a small amount of p-toluenesulfonic acid (PTSA).

4-(3-Oxo-4-morpholinyl)benzoic acid (CAS: 720720-60-5) is used in the pharmaceutical industry for the synthesis of drug intermediates and in the polymer industry as a monomer. It also finds applications in the sensor technology and semiconductor sectors due to its unique chemical properties.

When handling 4-(3-Oxo-4-morpholinyl)benzoic acid (CAS: 720720-60-5), it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be stored in a well-ventilated area away from direct sunlight and heat sources. In case of a spill, use appropriate containment measures and consult the Safety Data Sheet (SDS) for detailed instructions on cleanup procedures.