2-(1-Pyrrolidinyl)ethanamine

Basic Information

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CAS Number

7154-73-6

Molecular Formula

C6H14N2

Molecular Weight

114.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

66-70 °C/23 mmHg

Density

0.901 g/mL at 25 °C

Refractive Index

n20/D 1.468(lit.)

SMILES

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NCCN1CCCC1

InChI

InChI=1S/C6H14N2/c7-3-6-8-4-1-2-5-8/h1-7H2

InChIKey

WRXNJTBODVGDRY-UHFFFAOYSA-N

LogP

0.040899999999999714

Topological Polar Surface Area

29.259999999999998 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

57.5

Safety Information

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GHS Hazard Pictograms

H226

H314

Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 (3) Class 8 (3)

Sensitiveness

Air Sensitive

Synonyms & References

English

2-(Pyrrolidin-1-yl)ethanamine
1-pyrrolidineethanamine
2-(1-Pyrrolidinyl)ethanamine
2-(1-Pyrrolidinyl)ethylamine
2-Pyrrolidinoethylamine
Pyrrolidine, 1-(2-aminoethyl)-
Pyrrolidinoethanamine
Pyrrolidinoethylamine
1-(2-AMINOETHYL)PYRROLIDINE
2-pyrrolidin-1-ylethanamine
N-(2-aminoethyl)pyrrolidine
2-(1-Pyrrolidino)ethylamine
N-(2-Aminoethyl)pyrrolidine
2-(pyrrolidin-1-yl)ethan-1-amine

MDL Number

MFCD00003182

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 2-(1-Pyrrolidinyl)ethanamine (CAS: 7154-73-6)?

2-(1-Pyrrolidinyl)ethanamine (CAS: 7154-73-6) is a colorless or slightly yellowish liquid with a molecular weight of approximately 138.22 g/mol. It has a pKa of about 7.3 and is moderately soluble in water. This compound is highly reactive, particularly in basic conditions, and can undergo various chemical reactions such as nucleophilic substitution and amidation.

How is 2-(1-Pyrrolidinyl)ethanamine (CAS: 7154-73-6) typically synthesized?

2-(1-Pyrrolidinyl)ethanamine (CAS: 7154-73-6) is typically synthesized via the reaction of ethyl pyrrolidine-2-carboxylate with ammonia in the presence of a suitable base such as sodium hydroxide. The process involves a nucleophilic substitution reaction, yielding a high yield of the target compound.

What industries use 2-(1-Pyrrolidinyl)ethanamine (CAS: 7154-73-6)?

2-(1-Pyrrolidinyl)ethanamine (CAS: 7154-73-6) is primarily used in the pharmaceutical industry as a precursor for peptide synthesis. It is also utilized in the production of chelating agents, as a building block in the synthesis of polymers, and in the development of certain sensors and semiconductors.

What precautions should be taken when handling 2-(1-Pyrrolidinyl)ethanamine (CAS: 7154-73-6)?

When handling 2-(1-Pyrrolidinyl)ethanamine (CAS: 7154-73-6), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Storage should be in a cool, dry place away from direct sunlight and sources of ignition. Spills should be cleaned up using absorbent material and proper waste disposal procedures followed. Always consult the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.