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3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole(CAS: 864771-17-5)

3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
CAS Number

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Basic Information

Molecular Formula
C14H19BN2O2
Molecular Weight
258.13 g/mol

Physical Properties

Boiling Point
416.7 °C at 760 mmHg
Density
1.13
Flash Point
416.7 °C at 760 mmHg

Chemical Identifiers

SMILES
Cc1n[nH]c2ccc(cc12)B3OC(C)(C)C(C)(C)O3
InChIKey
YTYTZKVFIGWLKK-UHFFFAOYSA-N

Database References

MDL Number
MFCD07779192

FAQ

3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole (CAS: 864771-17-5) is a crystalline solid with a molecular weight of approximately 326.24 g/mol. It has moderate solubility in common organic solvents like dichloromethane and sulfolane. This compound is known for its reactivity in organoboron coupling reactions and its stability under standard laboratory conditions.
3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole (CAS: 864771-17-5) is usually synthesized via a Suzuki coupling reaction using 3-methyl-1H-indazole and 2-bromobutylboronic acid as starting materials. The reaction is typically catalyzed by palladium(II) acetate and a ligand such as Xantphos, with base like triphenylphosphine. High yields are achieved under mild conditions.
3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole (CAS: 864771-17-5) finds applications in the pharmaceutical industry, particularly in the synthesis of complex organic molecules. It is also used in the development of new materials and sensors, contributing to advancements in polymer science and electronic devices.
When handling 3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole (CAS: 864771-17-5), it is crucial to wear appropriate personal protective equipment (PPE) including gloves and safety goggles. The substance should be stored in a cool, dry place away from direct sunlight. In case of spill, use appropriate spill cleanup materials and ensure proper disposal. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

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