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Pazopanib(CAS: 444731-52-6)

Pazopanib
CAS Number

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Basic Information

Molecular Formula
C21H23N7O2S
Molecular Weight
437.53 g/mol
Physical State
Powder

Physical Properties

Melting Point
281-291°C
Boiling Point
728.8±70.0°C at 760 mmHg
Flash Point
359℃

Chemical Identifiers

SMILES
CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N
InChIKey
CUIHSIWYWATEQL-UHFFFAOYSA-N

Database References

MDL Number
MFCD11616589

FAQ

Pazopanib is a pharmaceutical compound with the CAS number 444731-52-6. It is a multi-kinase inhibitor used primarily in cancer treatment. Its chemical formula is C24H24N4O5S, and it is a white to off-white solid with good solubility in DMSO and methanol. Pazopanib is known for its ability to target various receptors involved in tumor growth and angiogenesis.
Pazopanib is mainly used in the treatment of advanced renal cell carcinoma and certain types of soft tissue sarcoma. It is also being researched for potential applications in other cancers, including breast, lung, and pancreatic cancer. As a kinase inhibitor, it is effective in blocking the signals that promote cancer cell proliferation and blood vessel formation, making it a valuable drug in oncology.
Pazopanib is generally considered safe when used as prescribed, but it may cause side effects such as fatigue, diarrhea, and hypertension. It is important to follow safety guidelines and consult healthcare professionals for proper handling. Safety standards are in place to ensure its use in controlled medical settings, and protective measures should be taken during storage and transportation to prevent exposure.
Pazopanib should be stored in a cool, dry place away from light. It is typically maintained at a temperature between 15°C to 25°C (59°F to 77°F) and should be kept in a sealed container to prevent moisture ingress. Proper storage ensures its stability and maintains potency, which is crucial for pharmaceutical quality and effectiveness.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

Contact Information

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