Compound Q&A

How is 3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole (CAS: 864771-17-5) typically synthesized?

Answer

3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole (CAS: 864771-17-5) is usually synthesized via a Suzuki coupling reaction using 3-methyl-1H-indazole and 2-bromobutylboronic acid as starting materials. The reaction is typically catalyzed by palladium(II) acetate and a ligand such as Xantphos, with base like triphenylphosphine. High yields are achieved under mild conditions.

About

English Name 3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
Molecular Formula C14H19BN2O2
Molecular Weight 258.13 g/mol
SMILES Cc1n[nH]c2ccc(cc12)B3OC(C)(C)C(C)(C)O3
InChIKey YTYTZKVFIGWLKK-UHFFFAOYSA-N
Last Updated: 2025-10-31 20:53

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