Ethyl 2-cyclopropyl-1,3-thiazole-4-carboxylate

Basic Information

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CAS Number

135207-08-8

Molecular Formula

C9H11NO2S

Molecular Weight

197.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

SMILES

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CCOC(=O)c1csc(n1)C2CC2

InChI

InChI=1S/C9H11NO2S/c1-2-12-9(11)7-5-13-8(10-7)6-3-4-6/h5-6H,2-4H2,1H3

InChIKey

GBKDQEYZOBSGCG-UHFFFAOYSA-N

LogP

2.1972000000000005

Topological Polar Surface Area

39.19 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Synonyms & References

English

ethyl 2-cyclopropylthiazole-4-carboxylate
6-Hydroxy-1,4-benzodioxane

MDL Number

MFCD22988964

FAQ

What are the physical and chemical properties of Ethyl 2-cyclopropyl-1,3-thiazole-4-carboxylate (CAS: 135207-08-8)?

Ethyl 2-cyclopropyl-1,3-thiazole-4-carboxylate (CAS: 135207-08-8) is a colorless to white crystalline solid with a molecular weight of approximately 226.27 g/mol. It has a pKa of around 4.2 and is soluble in organic solvents like ethanol and acetone but less soluble in water. The compound is relatively stable under normal conditions but can react with strong bases. It is used in various chemical reactions and synthetic pathways.

How is Ethyl 2-cyclopropyl-1,3-thiazole-4-carboxylate (CAS: 135207-08-8) typically synthesized?

Ethyl 2-cyclopropyl-1,3-thiazole-4-carboxylate (CAS: 135207-08-8) can be synthesized through a multi-step process that involves the reaction of 2-cyclopropyl-1,3-thiazole with ethyl chloroformate followed by hydrolysis. The reaction is typically carried out under mild conditions and can be catalyzed by a suitable acid or base. The yield can be enhanced by optimizing the reaction conditions and using appropriate solvents.

What industries use Ethyl 2-cyclopropyl-1,3-thiazole-4-carboxylate (CAS: 135207-08-8)?

Ethyl 2-cyclopropyl-1,3-thiazole-4-carboxylate (CAS: 135207-08-8) is used in the pharmaceutical industry for the synthesis of various organic compounds and in the production of certain medications. It also finds applications in the polymer industry for developing specific plastic materials and in the production of sensors and semiconductors for electronic devices.

What precautions should be taken when handling Ethyl 2-cyclopropyl-1,3-thiazole-4-carboxylate (CAS: 135207-08-8)?

When handling Ethyl 2-cyclopropyl-1,3-thiazole-4-carboxylate (CAS: 135207-08-8), it is important to use personal protective equipment (PPE) such as gloves and safety goggles. The compound should be handled in a fume hood to avoid inhalation. In case of a spill, it should be carefully cleaned up using appropriate absorbents. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.