Levocetirizine amide(CAS: 909779-33-5)

Levocetirizine amide (CAS: 909779-33-5) is a white to off-white crystalline powder. Its molecular weight is approximately 271.27 g/mol. It has a low solubility in water but is more soluble in organic solvents. Chemically, it is moderately reactive towards bases and is stable in acidic conditions. It undergoes hydrolysis under basic conditions and can react with nucleophiles.

Levocetirizine amide (CAS: 909779-33-5) is synthesized via amidation of levocetirizine with a suitable amine. The reaction is typically catalyzed by a coupling agent like HATU and is carried out in a polar aprotic solvent such as N,N-Dimethylformamide (DMF). The process is selective, with high yield and good purity.

Levocetirizine amide (CAS: 909779-33-5) is primarily used in the pharmaceutical industry for manufacturing antihistamine drugs. It is also applied in the chemical industry for its reactivity in various organic reactions. Additionally, it can be utilized in polymer and sensor applications due to its chemical properties.

When handling Levocetirizine amide (CAS: 909779-33-5), wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to avoid inhalation. Follow safe storage procedures, storing it in a cool, dry place away from direct sunlight. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.