Boc-Hoser(Bzl)-OH(CAS: 59408-74-1)

Boc-Hoser (Bzl)-OH (CAS: 59408-74-1) is a white crystalline solid with a molecular weight of approximately 236.36 g/mol. It has a solubility of about 0.2 g/100 mL in water and is soluble in methanol and acetonitrile. It is moderately reactive, particularly towards nucleophiles and bases, and can undergo esterification and amide formation reactions.

Boc-Hoser (Bzl)-OH (CAS: 59408-74-1) is synthesized from benzyl alcohol via a Boc-activation process. Commonly, benzyl alcohol is reacted with tert-butyldimethylsilyl chloride (TBSCl) and imidazole to form the corresponding silyl ether, which is then deprotonated and coupled with a carboxylic acid or amine to introduce the Boc group. This reaction typically yields 70-80% isolated purity.

Boc-Hoser (Bzl)-OH (CAS: 59408-74-1) is primarily used in the pharmaceutical and polymer industries. It serves as a protecting group in peptide and drug synthesis, and can also be used in the preparation of functional polymers and in sensor applications due to its reactivity and ease of incorporation into various molecular structures.

When handling Boc-Hoser (Bzl)-OH (CAS: 59408-74-1), appropriate personal protective equipment (PPE) should be worn, including gloves, safety goggles, and a lab coat. It should be stored in a cool, dry place away from sources of heat and light. Spills should be handled with care using appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for detailed spill cleanup instructions. Always work in a well-ventilated area or fume hood to minimize inhalation risk.