Boc-Hoser(Bzl)-OH

Basic Information

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CAS Number

59408-74-1

Molecular Formula

C16H23NO5

Molecular Weight

309.36 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Density

1.154

SMILES

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CC(C)(C)OC(=O)NC(CCOCC1=CC=CC=C1)C(=O)O

InChI

InChI=1S/C16H23NO5/c1-16(2,3)22-15(20)17-13(14(18)19)9-10-21-11-12-7-5-4-6-8-12/h4-8,13H,9-11H2,1-3H3,(H,17,20)(H,18,19)/t13-/m0/s1

InChIKey

RFDXPGUBDAKLDM-ZDUSSCGKSA-N

LogP

2.5712

Topological Polar Surface Area

84.86 Å²

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

358

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

(S)-4-benzyloxy-2-tert butoxycarbonylamino butyric acid
N-alpha-t-Butyloxycarbonyl-O-benzyl-L-homoserine
(S)-4-(benzyloxy)-2-(tert-butoxycarbonylamino)butanoic acid
O-Benzyl-N-(tert-butoxycarbonyl)-L-homoserine
DTXSID80567661
Homoserine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)-
C16046
Boc-O-benzyl-L-homoserine
(S)-4-(Benzyloxy)-2-((tert-butoxycarbonyl)amino)butanoic acid
59408-74-1
Boc-L-Hse(Bzl)-OH
(S)-4-Benzyloxy-2-tert-butoxycarbonylamino-butyric acid
Boc-Hoser(Bzl)-OH
AKOS015911587
boc-hse(bzl)-oh
CS-0127682
N-Boc-O-benzyl-L-homoserine
MFCD00270497
n-tert-butoxycarbonyl-o-benzyl-l-homoserine
DS-18583
(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-phenylmethoxybutanoic acid
(S)-4-benzyloxy-2-tertbutoxycarbonylaminobutyric acid
Boc-HomoSer(Bzl)-OH
O-benzyl-N-(tert-butoxycarbonyl)homoserine
RFDXPGUBDAKLDM-ZDUSSCGKSA-N
SCHEMBL955526
AM82565
L-Homoserine,N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)-
BOC-2-AMINO-4-BENZYLOXYBUTANOIC ACID
Boc-HoSer(Bzl)-OH
BOC-HSE(BZL)-OH

MDL Number

MFCD00270497

Customs Code

2924299090

FAQ

What are the physical and chemical properties of Boc-Hoser (Bzl)-OH (CAS: 59408-74-1)?

Boc-Hoser (Bzl)-OH (CAS: 59408-74-1) is a white crystalline solid with a molecular weight of approximately 236.36 g/mol. It has a solubility of about 0.2 g/100 mL in water and is soluble in methanol and acetonitrile. It is moderately reactive, particularly towards nucleophiles and bases, and can undergo esterification and amide formation reactions.

How is Boc-Hoser (Bzl)-OH (CAS: 59408-74-1) typically synthesized?

Boc-Hoser (Bzl)-OH (CAS: 59408-74-1) is synthesized from benzyl alcohol via a Boc-activation process. Commonly, benzyl alcohol is reacted with tert-butyldimethylsilyl chloride (TBSCl) and imidazole to form the corresponding silyl ether, which is then deprotonated and coupled with a carboxylic acid or amine to introduce the Boc group. This reaction typically yields 70-80% isolated purity.

What industries use Boc-Hoser (Bzl)-OH (CAS: 59408-74-1)?

Boc-Hoser (Bzl)-OH (CAS: 59408-74-1) is primarily used in the pharmaceutical and polymer industries. It serves as a protecting group in peptide and drug synthesis, and can also be used in the preparation of functional polymers and in sensor applications due to its reactivity and ease of incorporation into various molecular structures.

What precautions should be taken when handling Boc-Hoser (Bzl)-OH (CAS: 59408-74-1)?

When handling Boc-Hoser (Bzl)-OH (CAS: 59408-74-1), appropriate personal protective equipment (PPE) should be worn, including gloves, safety goggles, and a lab coat. It should be stored in a cool, dry place away from sources of heat and light. Spills should be handled with care using appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for detailed spill cleanup instructions. Always work in a well-ventilated area or fume hood to minimize inhalation risk.