Compound Q&A
How is Boc-Hoser (Bzl)-OH (CAS: 59408-74-1) typically synthesized?
Answer
Boc-Hoser (Bzl)-OH (CAS: 59408-74-1) is synthesized from benzyl alcohol via a Boc-activation process. Commonly, benzyl alcohol is reacted with tert-butyldimethylsilyl chloride (TBSCl) and imidazole to form the corresponding silyl ether, which is then deprotonated and coupled with a carboxylic acid or amine to introduce the Boc group. This reaction typically yields 70-80% isolated purity.
About
CAS No
59408-74-1
English Name
Boc-Hoser(Bzl)-OH
Molecular Formula
C16H23NO5
Molecular Weight
309.36 g/mol
SMILES
CC(C)(C)OC(=O)NC(CCOCC1=CC=CC=C1)C(=O)O
InChIKey
RFDXPGUBDAKLDM-ZDUSSCGKSA-N
Last Updated: 2025-10-22 19:24
