Z-D-Glu-OBzl | CAS No. 65706-99-2

Z-D-Glu-OBzl

Basic Information

View in Editor

CAS Number

65706-99-2

Molecular Formula

C20H21NO6

Molecular Weight

371.39 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

98.0 to 102.0 deg-C

Boiling Point

313.2 °C

Density

1.2680

Flash Point

313.2°C

Solubility

Soluble in methanol and acetic acid.

Refractive Index

1.575

SMILES

View in Editor

C1=CC=C(C=C1)COC(=O)C(CCC(=O)O)NC(=O)OCC2=CC=CC=C2

InChI

InChI=1S/C20H21NO6/c22-18(23)12-11-17(19(24)26-13-15-7-3-1-4-8-15)21-20(25)27-14-16-9-5-2-6-10-16/h1-10,17H,11-14H2,(H,21,25)(H,22,23)/t17-/m1/s1

InChIKey

VWHKODOUMSMUAF-QGZVFWFLSA-N

LogP

2.8896000000000015

Topological Polar Surface Area

101.93 Å²

Hydrogen Bond Donor/Acceptor

2 / 7

Complexity

483

Synonyms & References

English

MFCD00069647
1-Benzyl N-Carbobenzoxy-D-glutamate
Z-D-Glu-OBzl, >=98.0% (TLC)
N-Benzyloxycarbonyl-D-glutamic acid 1-benzyl ester
Z-D-Glu-OBzl
AMY25321
SCHEMBL2921260
(R)-5-(Benzyloxy)-4-(((benzyloxy)carbonyl)amino)-5-oxopentanoic acid
Q-101808
N-[(Phenylmethoxy)carbonyl]-D-glutamic Acid 1-(Phenylmethyl) Ester
Cbz-D-glutamic acid 1-benzyl ester
AKOS015924084
Cbz-D-Glu(OH)-O-Bzl
HY-W011075
N-Cbz-D-glutamic acid alpha-benzyl ester
(4R)-5-oxo-5-phenylmethoxy-4-(phenylmethoxycarbonylamino)pentanoic acid
1-Benzyl N-Cbz-D-glutamate
N-Carbobenzoxy-D-glutamic Acid 1-Benzyl Ester
CS-W011791
J-300119
DS-15304
Cbz-D-Glu-OCH2Ph
FD21463
B4281
Cbz-D-Glu-Obzl
Z-D-Glu-OBn
Cbz-D-Glu(OH)-OBzl
N-Cbz-D-glutamic Acid 1-Benzyl Ester
65706-99-2
VWHKODOUMSMUAF-QGZVFWFLSA-N
(R)-5-(benzyloxy)-4-(benzyloxycarbonylamino)-5-oxopentanoic acid

MDL Number

MFCD00069647

Customs Code

2924299090

FAQ

What are the physical and chemical properties of Z-D-Glu-OBzl (CAS: 65706-99-2)?

Z-D-Glu-OBzl (CAS: 65706-99-2) is a crystalline compound with a molecular weight of approximately 345.44 g/mol. It has a slightly soluble nature in water and a high solubility in organic solvents like methanol and acetone. This compound is reactive towards nucleophiles and can undergo esterification and amidation reactions. It exhibits good stability under basic conditions but is sensitive to strong acids.

How is Z-D-Glu-OBzl (CAS: 65706-99-2) typically synthesized?

Z-D-Glu-OBzl (CAS: 65706-99-2) is synthesized by acylating D-Glu (L-glutamic acid) with pentafluorophenyl ester and then coupling it with benzyl chloride in the presence of a base like triethylamine. The reaction proceeds with high selectivity and yields up to 90%, making it a reliable method for preparing this compound.

What industries use Z-D-Glu-OBzl (CAS: 65706-99-2)?

Z-D-Glu-OBzl (CAS: 65706-99-2) is used in the pharmaceutical industry for the synthesis of certain peptide drugs. It is also utilized in the polymer industry as a monomer for creating functional polymers. Additionally, it finds applications in the sensor industry for developing biosensors and in the semiconductor industry for modifying surfaces.

What precautions should be taken when handling Z-D-Glu-OBzl (CAS: 65706-99-2)?

When handling Z-D-Glu-OBzl (CAS: 65706-99-2), appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats should be worn. The compound should be stored in a fume hood to minimize inhalation risks. In case of a spill, it should be carefully cleaned up using absorbent materials. Always refer to the Material Safety Data Sheet (MSDS/SDS) for specific safety instructions and emergency procedures.