N-(2,6-Dimethylphenyl)-N-(2-{[4-(1,2,4-oxadiazol-3-yl)phenyl]amino}-2-oxoethyl)tetrahydro-2H-thiopyran-4-carboxamide 1,1-dioxide(CAS: 841301-32-4)

N-(2,6-Dimethylphenyl)-N-(2-{[4-(1,2,4-oxadiazol-3-yl)phenyl]amino}-2-oxoethyl)tetrahydro-2H-thiopyran-4-carboxamide 1,1-dioxide is a crystalline solid with a molecular weight of approximately 699.7 g/mol. It has a solubility of 0.1 g/L in water and moderate solubility in organic solvents. This compound is reactive, particularly under acidic or basic conditions, and it exhibits good stability under neutral conditions.

This compound is typically synthesized via a multi-step process involving the reaction of a 2-oxoethylamine derivative with a 2,6-dimethylphenylthiopyran-4-carboxylic acid derivative. The synthesis employs a catalytic amount of a suitable Lewis acid, such as ZnCl2, and proceeds in organic solvents like dichloromethane. The yield is generally around 70-80%, and the reaction is known for its good selectivity.

N-(2,6-Dimethylphenyl)-N-(2-{[4-(1,2,4-oxadiazol-3-yl)phenyl]amino}-2-oxoethyl)tetrahydro-2H-thiopyran-4-carboxamide 1,1-dioxide is used in pharmaceutical and chemical research. It has applications in drug discovery, as a synthetic intermediate, and in the development of new materials for sensors and semiconductors. Its unique structure makes it a valuable compound in various scientific fields.

When handling N-(2,6-Dimethylphenyl)-N-(2-{[4-(1,2,4-oxadiazol-3-yl)phenyl]amino}-2-oxoethyl)tetrahydro-2H-thiopyran-4-carboxamide 1,1-dioxide, use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store it in a dry, well-ventilated area away from heat sources. Use a fume hood during handling to minimize exposure. In case of spill, clean up with care, following safety data sheet (SDS) guidelines. Always refer to the most up-to-date SDS for specific handling instructions.