N-[5-Hydroxy-2,4-bis(2-methyl-2-propanyl)phenyl]-4-oxo-1,4-dihydro-3-quinolinecarboxamide | CAS No. 873054-44-5

N-[5-Hydroxy-2,4-bis(2-methyl-2-propanyl)phenyl]-4-oxo-1,4-dihydro-3-quinolinecarboxamide

Basic Information

CAS Number

873054-44-5

Molecular Formula

C24H28N2O3

Molecular Weight

392.5 g/mol

AD

Basic Physical Properties

CC(C)(C)c1cc(c(NC(=O)c2c[nH]c3ccccc3c2=O)cc1O)C(C)(C)C

InChI

InChI=1S/C24H28N2O3/c1-23(2,3)16-11-17(24(4,5)6)20(27)12-19(16)26-22(29)15-13-25-18-10-8-7-9-14(18)21(15)28/h7-13,27H,1-6H3,(H,25,28)(H,26,29)

InChIKey

PURKAOJPTOLRMP-UHFFFAOYSA-N

LogP

5.081000000000004

Topological Polar Surface Area

82.19 Ų

Hydrogen Bond Donor/Acceptor

3 / 5

Synonyms & References

English

  • VX770
  • Ivacaftor (VX-770)
  • N-[2,4-Bis(tert-butyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide
  • Ivacaftor
  • N-(2,4-ditert-butyl-5-hydroxyphenyl)-4-oxo-1H-quinoline-3-carboxamide
  • VX-770
  • [14C]-Ivacaftor
  • N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide
  • N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxaraide
  • UNII-1Y740ILL1Z
  • VX770,VX 770,Ivacaftor
  • N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxo-3-quinolinecarboxamide (ACI)
  • Kalydeco
  • N-(2,4-Di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide
  • N-(5-Hydroxy-2,4-di-tert-butylphenyl)-4-oxo-1H-quinoline-3-carboxamide
  • N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
  • N-[2,4-Di(tert-butyl)-5-hydroxyphenyl]-4-oxo-1H,4H-quinoline-3-carboxamide
  • VX 770

MDL Number

MFCD17171361

FAQ

What is N-[5-Hydroxy-2,4-bis(2-methyl-2-propanyl)phenyl]-4-oxo-1,4-dihydro-3-quinolinecarboxamide (CAS: 873054-44-5)?

N-[5-Hydroxy-2,4-bis(2-methyl-2-propanyl)phenyl]-4-oxo-1,4-dihydro-3-quinolinecarboxamide (CAS: 873054-44-5) is a complex organic compound characterized by its quinolinecarboxamide structure. It contains a hydroxy group and two isopropyl substituents on the phenyl ring. This compound is known for its potential pharmaceutical applications and is often used in research for drug development and chemical synthesis.

What are the main uses of N-[5-Hydroxy-2,4-bis(2-methyl-2-propanyl)phenyl]-4-oxo-1,4-dihydro-3-quinolinecarboxamide (CAS: 873054-44-5)?

N-[5-Hydroxy-2,4-bis(2-methyl-2-propanyl)phenyl]-4-oxo-1,4-dihydro-3-quinolinecarboxamide (CAS: 873054-44-5) is primarily used in pharmaceutical research as a potential inhibitor of certain enzymes. It may also find applications in the development of new drugs and as a building block in organic synthesis. Its unique structure makes it valuable for studying molecular interactions and biological activity.

Is N-[5-Hydroxy-2,4-bis(2-methyl-2-propanyl)phenyl]-4-oxo-1,4-dihydro-3-quinolinecarboxamide (CAS: 873054-44-5) safe?

N-[5-Hydroxy-2,4-bis(2-methyl-2-propanyl)phenyl]-4-oxo-1,4-dihydro-3-quinolinecarboxamide (CAS: 873054-44-5) should be handled with care, as it may have potential toxicity depending on exposure levels. Proper protective equipment, such as gloves and goggles, is recommended during handling. Safety data sheets (SDS) should be consulted for detailed information on health and safety protocols.

How should N-[5-Hydroxy-2,4-bis(2-methyl-2-propanyl)phenyl]-4-oxo-1,4-dihydro-3-quinolinecarboxamide (CAS: 873054-44-5) be stored?

N-[5-Hydroxy-2,4-bis(2-methyl-2-propanyl)phenyl]-4-oxo-1,4-dihydro-3-quinolinecarboxamide (CAS: 873054-44-5) should be stored in a cool, dry, and dark place, away from moisture and light. It is recommended to keep it in a sealed container at a temperature below 25°C to maintain stability and prevent degradation.

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