1-{2-Chloro-4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl}-3-(5-methyl-1,2-oxazol-3-yl)urea

Basic Information

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CAS Number

475108-18-0

Molecular Formula

C22H19ClN4O5

Molecular Weight

454.87 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

208-213°C

Boiling Point

550.4±50.0°C at 760 mmHg

SMILES

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CC1=CC(=NO1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)Cl

InChI

InChI=1S/C22H19ClN4O5/c1-12-8-21(27-32-12)26-22(28)25-16-5-4-13(9-15(16)23)31-18-6-7-24-17-11-20(30-3)19(29-2)10-14(17)18/h4-11H,1-3H3,(H2,25,26,27,28)

InChIKey

SPMVMDHWKHCIDT-UHFFFAOYSA-N

LogP

5.6381200000000025

Topological Polar Surface Area

107.74000000000001 Å²

Hydrogen Bond Donor/Acceptor

2 / 9

Complexity

631

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

A24970
HMS3654G22
BCP01980
1-{2-chloro-4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-3-[(3E)-5-methylisoxazol-3(2H)-ylidene]urea
AV-951
Urea, N-(2-chloro-4-((6,7-dimethoxy-4-quinolinyl)oxy)phenyl)-N'-(5-methyl-3-isoxazolyl)-
KRN951
BRD-K53414658-001-01-7
VEGFR Tyrosine Kinase Inhibitor IV
MLS006011287
D09683
HMS3265A11
AV951 (KRN951, TIVOZANIB)
KRN 951
AV 951
AC-24702
BCP9000343
1-(2-Chloro-4-((6,7-dimethoxyquinolin-4-yl)-oxy)phenyl)-3-(5-methylisoxazol-3-yl)urea
N-[2-CHLORO-4-[(6,7-DIMETHOXY-4-QUINOLYL)OXY]PHENYL]-N'-(5-METHYL-3-ISOXAZOLYL)UREA
AV951
1-{2-chloro-4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-3-(5-methyl-1,2-oxazol-3-yl)urea
HMS3244C19
N-(2-Chloro-4-((6,7-dimethoxy-4-quinolyl)oxy)phenyl)-N'-(5-methyl-3-isoxazolyl)urea
MFCD15146788
tivozanibum
CHEBI:91327
AV9
HMS3229O09
HMS3265A12
N-(2-CHLORO-4-((6,7-DIMETHOXYQUINOLIN-4-YL)OXY)PHENYL)-N'-(5-METHYLISOXAZOL-3-YL)UREA
1-(2-chloro-4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)-3-(5-methylisoxazol-3-yl)urea;AV-951

MDL Number

MFCD15146788

FAQ

What is 1-{2-Chloro-4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl}-3-(5-methyl-1,2-oxazol-3-yl)urea (CAS: 475108-18-0)?

1-{2-Chloro-4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl}-3-(5-methyl-1,2-oxazol-3-yl)urea is a complex organic molecule with potential pharmaceutical applications. It consists of a quinoline ring system and a urea moiety. The compound is characterized by its aromatic and heterocyclic structure.

What are the main uses of 1-{2-Chloro-4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl}-3-(5-methyl-1,2-oxazol-3-yl)urea (CAS: 475108-18-0)?

This compound may be used as an intermediate or precursor in the synthesis of other pharmaceuticals and is potentially useful in the development of new drugs. Its specific applications may include anti-inflammatory, antiviral, or anticancer properties.

Is 1-{2-Chloro-4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl}-3-(5-methyl-1,2-oxazol-3-yl)urea (CAS: 475108-18-0) safe?

Safety data for this compound is limited. It is important to follow safety guidelines and use proper personal protective equipment (PPE) during handling. Ensure compliance with local regulations and workplace safety standards. Exposure routes should be minimized, and appropriate ventilation should be maintained.

How should 1-{2-Chloro-4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl}-3-(5-methyl-1,2-oxazol-3-yl)urea (CAS: 475108-18-0) be stored?

Store the compound in a cool, dry place away from direct sunlight and heat sources. Maintain a temperature range of 15-25°C and store in a tightly sealed container to prevent degradation. Avoid contact with water and moisture. Handle with care to prevent spillage or contamination.

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Compound Q&A

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Compound Q&A

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1-{2-Chloro-4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl}-3-(5-methyl-1,2-oxazol-3-yl)urea | CAS No. 475108-18-0

Basic Information

CAS Number

Molecular Formula

Molecular Weight

Chemical Classification

Basic Physical Properties

Melting Point

Boiling Point

Chemical Properties

SMILES

InChI

InChIKey

LogP

Topological Polar Surface Area

Hydrogen Bond Donor/Acceptor

Complexity

Safety Information

Hazard Statement

Synonyms & References

English

MDL Number

FAQ

What is 1-{2-Chloro-4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl}-3-(5-methyl-1,2-oxazol-3-yl)urea (CAS: 475108-18-0)?

What are the main uses of 1-{2-Chloro-4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl}-3-(5-methyl-1,2-oxazol-3-yl)urea (CAS: 475108-18-0)?

Is 1-{2-Chloro-4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl}-3-(5-methyl-1,2-oxazol-3-yl)urea (CAS: 475108-18-0) safe?

How should 1-{2-Chloro-4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl}-3-(5-methyl-1,2-oxazol-3-yl)urea (CAS: 475108-18-0) be stored?

Related Compounds

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