2,5-Dioxo-1-pyrrolidinyl 1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-prolinate | CAS No. 3392-10-7

2,5-Dioxo-1-pyrrolidinyl 1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-prolinate

Basic Information

CAS Number

3392-10-7

Molecular Formula

C14H20N2O6

Molecular Weight

312.32 g/mol

AD

Basic Physical Properties

Melting Point

133-135 °C

Boiling Point

421.3°Cat760mmHg

Density

1.32

Flash Point

208.6°C

Refractive Index

1.542

CC(C)(C)OC(=O)N1CCCC1C(=O)ON2C(=O)CCC2=O

InChI

InChI=1S/C14H20N2O6/c1-14(2,3)21-13(20)15-8-4-5-9(15)12(19)22-16-10(17)6-7-11(16)18/h9H,4-8H2,1-3H3/t9-/m0/s1

InChIKey

DICWIJISMKZDDY-VIFPVBQESA-N

LogP

0.9930999999999999

Topological Polar Surface Area

93.22 Ų

Hydrogen Bond Donor/Acceptor

0 / 8

Complexity

494

Synonyms & References

English

  • SCHEMBL4959104
  • (S)-Pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-(2,5-dioxo-pyrrolidin-1-yl) ester
  • Boc-Pro-OSu, >=98.0% (N)
  • J-019382
  • 2,5-Dioxopyrrolidin-1-yl 1-(tert-butoxycarbonyl)-L-prolinate
  • Boc-L-Proline hydroxysuccinimide ester
  • DICWIJISMKZDDY-VIFPVBQESA-N
  • MFCD00037902
  • Boc-Pro-OSu
  • F10848
  • N-alpha-t-Butyloxycarbonyl-L-proline succinimidyl ester
  • AS-46894
  • BocProOSu
  • 2,3,4,6-tetraacetyl-
  • N-t-Boc-L-proline-N-hydroxysuccinimide Ester
  • (S)-1-tert-butyl 2-(2,5-dioxopyrrolidin-1-yl) pyrrolidine-1,2-dicarboxylate
  • NS00049281
  • AKOS016843122
  • A-d-glucose
  • 3392-10-7
  • 1,2-Pyrrolidinedicarboxylicacid, 1-(1,1-dimethylethyl) 2-(2,5-dioxo-1-pyrrolidinyl) ester, (2S)-
  • 1,2-Pyrrolidinedicarboxylicacid, 1-(1,1-dimethylethyl) 2-(2,5-dioxo-1-pyrrolidinyl) ester, (2S...
  • Boc-L-Pro-Osu
  • BOC-L-PROLINE HYDROXYSUCCINIMIDE ESTER
  • BOC-L-PROLINE HYDROXYSUCCINIMIDESTER
  • BOC-L-PROLINE-OSU
  • Boc-Pro-ONSu
  • N-(t-butyloxycarbonyl)-L-proline succinimidyl ester
  • N-(tert-butoxycarbonyl)-(L)-pr
  • N-Boc-L-Proline succinimidyl ester
  • N-tert-butoxycarbonylprolyl-N-hydroxysuccinimide ester

MDL Number

MFCD00037902

Customs Code

2925190090

FAQ

What are the physical and chemical properties of 2,5-Dioxo-1-pyrrolidinyl 1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-prolinate (CAS: 3392-10-7)?

2,5-Dioxo-1-pyrrolidinyl 1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-prolinate is a white crystalline solid with a molecular weight of approximately 328.45 g/mol. It is slightly soluble in water but highly soluble in organic solvents. The compound is relatively stable but can react with strong bases. It has a pKa of about 3.8. It is used as an intermediate in the synthesis of other organic compounds and pharmaceuticals.

How is 2,5-Dioxo-1-pyrrolidinyl 1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-prolinate (CAS: 3392-10-7) typically synthesized?

2,5-Dioxo-1-pyrrolidinyl 1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-prolinate is synthesized through a multi-step process involving the protection of L-proline, followed by acylation, cyclization, and deprotection. Common catalysts include acid catalysts like acetic anhydride. The reaction yield is typically high, around 90%, and the method is highly selective.

What industries use 2,5-Dioxo-1-pyrrolidinyl 1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-prolinate (CAS: 3392-10-7)?

2,5-Dioxo-1-pyrrolidinyl 1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-prolinate is primarily used in the pharmaceutical industry as an intermediate for the synthesis of various drugs. It is also used in the polymer industry for the development of advanced materials and in the sensor industry for biosensing applications.

What precautions should be taken when handling 2,5-Dioxo-1-pyrrolidinyl 1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-prolinate (CAS: 3392-10-7)?

When handling 2,5-Dioxo-1-pyrrolidinyl 1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-prolinate, appropriate personal protective equipment (PPE) should be worn, including gloves and safety goggles. It should be stored in a cool, dry, and well-ventilated area. In case of spill, it should be cleaned up using appropriate absorbents and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.

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