5-Hydroxy Diclofenac(CAS: 69002-84-2)

5-Hydroxy Diclofenac (CAS: 69002-84-2) is a white to off-white crystalline solid with a molecular weight of approximately 270.26 g/mol. It is slightly soluble in water and more soluble in organic solvents. Chemically, it is highly reactive, particularly with bases and reducing agents. It is stable under normal storage conditions but should be protected from moisture and light.

5-Hydroxy Diclofenac (CAS: 69002-84-2) is synthesized by the reduction of 2,3-dichlorobenzoic acid with sodium borohydride, followed by acylation and hydroxylation steps. The process is carried out in organic solvents like methanol or ethanol. Catalysts such as sodium hydride are used to improve selectivity and yield. The final product is isolated through recrystallization from suitable solvents.

5-Hydroxy Diclofenac (CAS: 69002-84-2) is primarily used in the pharmaceutical industry for the development of anti-inflammatory and analgesic drugs. It is also explored in research for its potential use in other applications such as polymer synthesis and sensor technology.

When handling 5-Hydroxy Diclofenac (CAS: 69002-84-2), it is essential to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated environment or a fume hood. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Refer to the safety data sheet (SDS) for detailed handling and safety information.