Compound Q&A
How is 5-Hydroxy Diclofenac (CAS: 69002-84-2) typically synthesized?
Answer
5-Hydroxy Diclofenac (CAS: 69002-84-2) is synthesized by the reduction of 2,3-dichlorobenzoic acid with sodium borohydride, followed by acylation and hydroxylation steps. The process is carried out in organic solvents like methanol or ethanol. Catalysts such as sodium hydride are used to improve selectivity and yield. The final product is isolated through recrystallization from suitable solvents.
About
CAS No
69002-84-2
English Name
5-Hydroxy Diclofenac
Molecular Formula
C14H11Cl2NO3
Molecular Weight
312.1 g/mol
SMILES
C1=CC(=C(C(=C1)Cl)NC2=C(C=C(C=C2)O)CC(=O)O)Cl
InChIKey
VNQURRWYKFZKJZ-UHFFFAOYSA-N
Last Updated: 2025-11-05 07:29
