The application of nanoparticles based on ferroptosis in cancer therapy

Literature Information

Publication Date 2023-12-08
DOI 10.1039/D3TB02308G
Impact Factor 6.331
Authors

Yifei Li, Chen Wei, Jianqin Yan, Fashun Li, Bohan Chen, Yong Sun, Kui Luo, Bin He, Yan Liang


View Original

Abstract

Ferroptosis is a new form of non-apoptotic programmed cell death. Due to its effectiveness in cancer treatment, there are increasing studies on the application of nanoparticles based on ferroptosis in cancer therapy. In this paper, we present a summary of the latest progress in nanoparticles based on ferroptosis for effective tumor therapy. We also describe the combined treatment of ferroptosis with other therapies, including chemotherapy, radiotherapy, phototherapy, immunotherapy, and gene therapy. This summary of drug delivery systems based on ferroptosis aims to provide a basis and inspire opinions for researchers concentrating on exploring this field. Finally, we present some prospects and challenges for the application of nanotherapies to clinical treatment by promoting ferroptosis in cancer cells.

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