Rh(iii)-catalyzed selective mono- and dual-functionalization/cyclization of 1-aryl-5-aminopyrazoles with iodonium ylides

Literature Information

Publication Date 2023-12-05
DOI 10.1039/D3CC05266D
Impact Factor 6.222
Authors

Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang


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Abstract

An efficient Rh(III)-catalyzed selective mono- and dual-C–H bond functionalization/cyclization with iodonium ylide as a single coupling partner was demonstrated, in which fused benzodiazepine skeletons were obtained in excellent yields. This method greatly improved an effective approach to dual C–H unsymmetrical functionalization.

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