6-Chloro-5-(2'-hydroxy-3'-methoxy-4-biphenylyl)-3-(3-methoxyphenyl)-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione | CAS No. 1346607-05-3

6-Chloro-5-(2'-hydroxy-3'-methoxy-4-biphenylyl)-3-(3-methoxyphenyl)-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione

Basic Information

CAS Number

1346607-05-3

Molecular Formula

C26H20ClN3O5

Molecular Weight

489.92 g/mol

AD

Basic Physical Properties

COc1cccc(c1)n2c(=O)c3c(cc(n3c4ccc(cc4)c5cccc(c5O)OC)Cl)[nH]c2=O

InChI

InChI=1S/C26H20ClN3O5/c1-34-18-6-3-5-17(13-18)30-25(32)23-20(28-26(30)33)14-22(27)29(23)16-11-9-15(10-12-16)19-7-4-8-21(35-2)24(19)31/h3-14,31H,1-2H3,(H,28,33)

InChIKey

KURYSXLJGKKDHT-UHFFFAOYSA-N

LogP

4.512900000000003

Topological Polar Surface Area

98.47999999999999 Ų

Hydrogen Bond Donor/Acceptor

2 / 8

Synonyms & References

English

  • GSK621
  • 6-Chloro-5-(2′-hydroxy-3′-methoxy-[1,1′-biphenyl]-4-yl)-3-(3-methoxyphenyl)-1,5-dihydro-2H-pyrrolo[3,2-d]pyrimidine-2,4(3H)-dione
  • 6-Chloro-5-(2′-hydroxy-3′-methoxy[1,1′-biphenyl]-4-yl)-3-(3-methoxyphenyl)-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione

MDL Number

MFCD28502280

FAQ

What regulatory guidelines apply to 6-Chloro-5-(2'-hydroxy-3'-methoxy-4-biphenylyl)-3-(3-methoxyphenyl)-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione (CAS: 1346607-05-3)?

The compound 6-Chloro-5-(2'-hydroxy-3'-methoxy-4-biphenylyl)-3-(3-methoxyphenyl)-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione (CAS: 1346607-05-3) should comply with the REACH regulations for chemical substances registration, evaluation, authorization, and restriction in the European Union. In the U.S., it should meet the requirements of the Toxic Substances Control Act (TSCA) and the EPA for chemical management. Additionally, proper GHS (Globally Harmonized System of Classification and Labeling of Chemicals) classification and labeling must be followed for transportation and storage.

Are there alternatives to 6-Chloro-5-(2'-hydroxy-3'-methoxy-4-biphenylyl)-3-(3-methoxyphenyl)-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione (CAS: 1346607-05-3) in synthesis?

For the synthesis of 6-Chloro-5-(2'-hydroxy-3'-methoxy-4-biphenylyl)-3-(3-methoxyphenyl)-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione (CAS: 1346607-05-3), there are a few alternatives such as using related pyrimidine derivatives or similar 5,6-disubstituted pyrimidines. Common alternative reagents like chlorination agents, methylation reagents, and coupling reagents can be considered. However, the choice of alternative depends on the specific reaction conditions and desired product properties.

What is the market or research trend for 6-Chloro-5-(2'-hydroxy-3'-methoxy-4-biphenylyl)-3-(3-methoxyphenyl)-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione (CAS: 1346607-05-3)?

The market for 6-Chloro-5-(2'-hydroxy-3'-methoxy-4-biphenylyl)-3-(3-methoxyphenyl)-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione (CAS: 1346607-05-3) is currently driven by its applications in the pharmaceutical and agrochemical sectors. Research trends indicate a focus on developing new drug candidates and agrochemicals with enhanced efficacy and reduced side effects. Additionally, there is an increasing interest in studying its biological activity and potential therapeutic applications.

How should waste containing 6-Chloro-5-(2'-hydroxy-3'-methoxy-4-biphenylyl)-3-(3-methoxyphenyl)-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione (CAS: 1346607-05-3) be handled?

Waste containing 6-Chloro-5-(2'-hydroxy-3'-methoxy-4-biphenylyl)-3-(3-methoxyphenyl)-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione (CAS: 1346607-05-3) should be collected in appropriate containers and labeled with a hazardous waste symbol. It should then be handled according to local waste regulations. If possible, the waste should be incinerated or disposed of through professional waste disposal services. Environmental protection precautions include ensuring no leakage and using personal protective equipment during handling and disposal to prevent exposure and environmental contamination.

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