The advanced synthetic modifications and applications of multifunctional PAMAM dendritic composites

The profound advances in dendrimer chemistry have led to new horizons in polymer science. Moreover, this has promisingly uncovered opportunities to develop new versatile polymers in the form of poly(amidoamine) dendrimer hybrids to utilize their intrinsic distinctive properties. The unique three-dimensional globular shape, highly branched structure, monodispersity, controlled topology, nanoarchitecture, and massive number of cavities have spurred polymer researchers to construct new poly(amidoamine) dendrimer composites using organic and inorganic materials. Thus, to meet the prospective needs of modern scientific research, significant efforts have been made to functionalize PAMAM, encompassing applications in the biomedical and non-biomedical areas. This review article attempts to consolidate the research work to date relating to the synthesis of organic/inorganic hybrids of poly(amidoamine) dendrimers and their potential applications in the biomedical field, controlled agrochemical release, catalysis, wastewater treatment, imaging, biosensors, etc.