![(2S)-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}(phenyl)acetic acid structure](https://static.chemtradehub.com/structs/102/102410-65-1-4aa7.webp "(2S)-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}(phenyl)acetic acid structure")
(2S)-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}(phenyl)acetic acid
CAS Number:
102410-65-1
Molecular Formula:
C23H19NO4
Development of a lateral flow test for rapid pyrethroid detection using antibody-gated indicator-releasing hybrid materials
Literature Information
Publication Date
2020-04-06
DOI
10.1039/D0AN00319K
Impact Factor
4.616
Authors
Elena Costa, Estela Climent, Sandra Ast, Michael G. Weller, John Canning, Knut Rurack
View Original
Abstract
The employment of type-I pyrethroids for airplane disinfection in recent years underlines the necessity to develop sensing schemes for the rapid detection of these pesticides directly at the point-of-use. Antibody-gated indicator-releasing materials were thus developed and implemented with test strips for lateral-flow assay-based analysis employing a smartphone for readout. Besides a proper matching of pore sizes and gating macromolecules, the functionalization of both the material's outer surface as well as the strips with PEG chains enhanced system performance. This simple assay allowed for the detection of permethrin as a target molecule at concentrations down to the lower ppb level in less than 5 minutes.
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Source Journal
Analyst
CiteScore:
7.8
Self-citation Rate:
5.6%
Articles per Year:
653
Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.
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