First synthesis of orthogonally 1,7-diprotected cyclens

Literature Information

Publication Date 2019-03-20
DOI 10.1039/C9QO00184K
Impact Factor 5.281
Authors

Luciano Lattuada, Giovanni B. Giovenzana


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Abstract

The first examples of 1,7-orthogonally diprotected cyclen (1,4,7,10-tetraazacyclododecane) derivatives have been prepared through a straightforward and convenient synthetic strategy. These compounds represent useful starting materials for the preparation of several functionalised macrocyclic chelating agents.

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Organic Chemistry Frontiers

Organic Chemistry Frontiers
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Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry

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