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Catalyst-free oxidative N–N coupling for the synthesis of 1,2,3-triazole compounds with tBuONO
Literature Information
Publication Date
2019-03-19
DOI
10.1039/C9QO00071B
Impact Factor
5.281
Authors
Yue-Ming Cai, Xin Zhang, Cui An, Ye-Fei Yang, Wei Liu, Wen-Xia Gao, Xiao-Bo Huang, Yun-Bing Zhou, Miao-Chang Liu, Hua-Yue Wu
View Original
Abstract
We disclose a catalyst-free method to synthesize 1,2,3-triazoles rapidly via an oxidative N–N coupling strategy. Of particular note is that the one-step synthesis route to access [1,2,3]triazolo[1,5-a]pyridines from pyridin-2-ylmethanamine has been reported for the first time. This approach features no use of catalyst, extremely mild conditions and excellent efficiency.
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Source Journal
Organic Chemistry Frontiers
CiteScore:
7.8
Self-citation Rate:
8.7%
Articles per Year:
724
Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry
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