Structure elucidation of bacterial nonribosomal lipopeptides
Literature Information
Sebastian Götze, Pierre Stallforth
Nonribosomal lipopeptides (NRLPs) are complex natural products of bacterial origin that not only fulfill important ecological functions but also serve as lead structures for the development of new pharmaceuticals. In order to carry out detailed structure–activity relationship studies and to decipher the biological activities of NRLPs, the primary structure, including stereochemical assignment, of every new member of this natural product family has to be established first. In this review, we want to focus on analytical techniques and tools that can be employed to elucidate the structure of bacterial NRLPs.
Recommended Journals
Related Literature
Combining CROP and ATRP to synthesize pH-responsive poly(2-ethyl-2-oxazoline-b-4-vinylpyridine) block copolymers
Rafael Natal Lima de Menezes, Maria Isabel Felisberti
DOI: 10.1039/D1PY00730K
Blue light driven free-radical polymerization using arylazo sulfones as initiators
Andrea Nitti, Angelo Martinelli, Fabrice Batteux, Stefano Protti, Maurizio Fagnoni, Dario Pasini
DOI: 10.1039/D1PY00928A
Structural transformation sequence occurring during the activation under n-butane–air of a cobalt-doped vanadium phosphate hemihydrate precursor for mild oxidation to maleic anhydride
Sujata Sajip, Jonathan K. Bartley, Andrew Burrows, Colin Rhodes, Jean Claude Volta, Christopher J. Kiely, Graham J. Hutchings
DOI: 10.1039/B102324C
The effects of cononsolvents on the synthesis of responsive particles via polymerisation-induced thermal self-assembly
Marissa D. Morales-Moctezuma, Sebastian G. Spain
DOI: 10.1039/D1PY00396H
Theoretical and experimental approaches to evaluate the intermolecular hydrogen-bonding ability of tertiary amides
Kun-Young Kim, Ho-Jin Lee, Alfred Karpfen, Jeunghee Park, Chang-Ju Yoon, Young-Sang Choi
DOI: 10.1039/B101187L
Merging of cationic RAFT and radical RAFT polymerizations with ring-opening polymerizations for the synthesis of asymmetric ABCD type tetrablock copolymers in one pot
Yuejia Zhu, Luoyu Gao, Zhenjiang Li, Bo Liu, Zhihao Zhang, Haoying Tong, Yuanyuan Qu, Yusheng Quan, Xin Zou, Kai Guo
DOI: 10.1039/D1PY00971K
Theoretical study of cyanophosphapropyne (NCCP), isocyanophosphapropyne (CNCP) and their isomers: stability and properties
Tamás Veszprémi, Minh Tho Nguyen
DOI: 10.1039/B100463H
ATR-IR spectroscopy at the metal–liquid interface: influence of film properties on anomalous band-shape
DOI: 10.1039/B101218P
You might also like
What regulatory guidelines apply to 6-Bromo-2-methylimidazo[1,2-a]pyrimidine (CAS: 1111638-05-1)?
6-Bromo-2-methylimidazo[1,2-a]pyrimidine (CAS: 1111638-05-1) falls under various...
Are there alternatives to 1-Pyrrolidineethanol, β-methyl-α-phenyl-, (αS,βR) (CAS: 123620-80-4) in synthesis?
While there are no direct alternatives, similar compounds like 1-Pyrrolidineetha...
Is 4-Methyl-2,6-bis(2-methyl-2-propanyl)phenyl methylcarbamate (CAS: 1918-11-2) safe?
4-Methyl-2,6-bis(2-methyl-2-propanyl)phenyl methylcarbamate (CAS: 1918-11-2) is ...
How should 2-(3-Bromo-4-fluorophenyl)-1,3-dioxolane (CAS: 77771-04-1) be stored?
2-(3-Bromo-4-fluorophenyl)-1,3-dioxolane (CAS: 77771-04-1) should be stored in a...
What are the physical and chemical properties of 4,5,6,7-Tetrahydro-1H-indazole hydrochloride (CAS: 18161-11-0)?
4,5,6,7-Tetrahydro-1H-indazole hydrochloride is a white crystalline solid with a...
What is (2R)-1-Methoxy-3-phenyl-2-propanamine (CAS: 59919-07-2)?
(2R)-1-Methoxy-3-phenyl-2-propanamine is a chiral organic compound with the CAS ...
What industries use Ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate (CAS: 56649-47-9)?
Ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate is used in various industries...
What regulatory guidelines apply to 4-[(1E,3S)-1-(4-Hydroxyphenyl)-1,4-pentadien-3-yl]phenol (CAS: 17676-24-3)?
4-[(1E,3S)-1-(4-Hydroxyphenyl)-1,4-pentadien-3-yl]phenol (CAS: 17676-24-3) falls...
What industries use (S)-3-Amino-5-phenylpentanoic acid hydrochloride (CAS: 331846-97-0)?
(S)-3-Amino-5-phenylpentanoic acid hydrochloride is primarily used in the pharma...
How is 7-methoxy-1-benzothiophene-2-carboxylic acid (CAS: 88791-07-5) typically synthesized?
7-Methoxy-1-benzothiophene-2-carboxylic acid is typically synthesized by reactin...
Source Journal
Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.














