Chitosan/rectorite nanocomposite with injectable functionality for skin hemostasis
Literature Information
Xiaoyun Li, Yi-Chen Li, Mingjie Chen, Qingshan Shi, Runcang Sun, Xiaoying Wang
Many animals such as snails and Chinese giant salamanders can secrete mucus for moisturizing, eliminating swelling and inflammation, and promoting wound healing; this implies that high viscous bio-functional materials inspired by mucus may show potential for biomedical applications. Herein, we developed a maltose-like injectable nanocomposite via the combination of chitosan polysaccharide and clay rectorite for hemostasis. Through the hemostatic property of rectorite, the viscous nanocomposite decreased the in vitro clotting time by 43%. Moreover, an in vitro porcine skin model confirmed that the viscous nanocomposite can stably adhere on skin and impede blood bleeding successfully. Importantly, the internal structure of the nanocomposites, chitosan intercalating into rectorite interlayers, provided a physical cross-linked network to decrease the release of rectorite from the nanocomposite and its invasion into the blood. Therefore, this viscous injectable nanocomposite provided a concept for a facile and sustainable biomaterial for skin hemostasis.
Recommended Journals
Related Literature
ATRP–RCMpolymercyclization: synthesis of amphiphilic cyclic polystyrene-b-poly(ethylene oxide) copolymers
Eisuke Baba, Satoshi Honda, Takuya Yamamoto, Yasuyuki Tezuka
DOI: 10.1039/C1PY00475A
Fast and scalable production of hyperbranched polythioether-ynes by a combination of thiol-halogen click-like coupling and thiol-yne click polymerization
Jin Han, Bo Zhao, Aijin Tang, Yanqin Gao, Chao Gao
DOI: 10.1039/C1PY00367D
Naphtho[1,2-b:5,6-b′]dithiophene-based conjugated polymer as a new electron donor for bulk heterojunction organic solar cells
Pranabesh Dutta, Hanok Park, Woo-Hyung Lee, Kyuri Kim, In Nam Kang, Soo-Hyoung Lee
DOI: 10.1039/C2PY00424K
A new story of cyclodextrin as a bulky pendent group causing uncommon behaviour to random copolymers in solution
Fuji Sakai, Guosong Chen, Ming Jiang
DOI: 10.1039/C2PY00614F
Synthesis of cyclic amphiphilic homopolymers and their potential application as polymeric micelles
Boyd A. Laurent, Scott M. Grayson
DOI: 10.1039/C1PY00378J
Poly(ethylene) brushes grafted to silicon substrates
Denis Damiron, Jérôme Mazzolini, Fabrice Cousin, Christophe Boisson, Franck D'Agosto, Eric Drockenmuller
DOI: 10.1039/C1PY00459J
Amphiphilic diblock copolymers based on ethylene oxide and epoxides bearing aliphatic side chains
Stergios Pispas
DOI: 10.1039/C2PY20189E
Cyclopenta[c]thiophene oligomers based solution processable D–A copolymers and their application as FET materials
Anjan Bedi, Satyaprasad P. Senanayak, Soumyajit Das, K. S. Narayan, Sanjio S. Zade
DOI: 10.1039/C2PY20032E
Rapidly thiol-responsive degradable block copolymer nanocarriers with facile bioconjugation
Samuel Aleksanian, Behnoush Khorsand, Rolf Schmidt, Jung Kwon Oh
DOI: 10.1039/C2PY20154B
You might also like
Are there alternatives to 1-(4-Chlorophenyl)-N-hydroxymethanimine (CAS: 3848-36-0) in synthesis?
When considering alternatives to 1-(4-Chlorophenyl)-N-hydroxymethanimine (CAS: 3...
How should (1R,9S,10S,12S,14E,16S,19R,20R,21S,22R)-3,9,21-Trihydroxy-5,10,12,14,16,20,22-heptamethyl-23,24-dioxatetracyclo[17.3.1.1~6,9~.0~2,7~]tetracosa-2,5,7,14-tetraen-4-one (CAS: 183202-73-5) be stored?
This compound should be stored in a cool, dry place away from direct sunlight. I...
How is 3-(4-Bromophenyl)-5-(2-fluorophenyl)-1,2,4-oxadiazole (CAS: 419553-16-5) typically synthesized?
3-(4-Bromophenyl)-5-(2-fluorophenyl)-1,2,4-oxadiazole is synthesized through a m...
How is 5-Chloro-2-(4-chlorophenyl)-4-methyl-6-[3-(1-piperidinyl)propoxy]pyrimidine (CAS: 1639220-19-1) typically synthesized?
5-Chloro-2-(4-chlorophenyl)-4-methyl-6-[3-(1-piperidinyl)propoxy]pyrimidine (CAS...
What industries use 2-Chloro-4-(difluoromethoxy)pyridine (CAS: 1206978-15-5)?
2-Chloro-4-(difluoromethoxy)pyridine is used in the pharmaceutical industry for ...
What regulatory guidelines apply to 3-Chloro-6-methylpyridazine (CAS: 1121-79-5)?
3-Chloro-6-methylpyridazine (CAS: 1121-79-5) is classified under the Globally Ha...
Are there alternatives to Methyl 4,5-dimethyl-2-nitrobenzoate in synthesis?
Several alternatives can be used in the synthesis of Methyl 4,5-dimethyl-2-nitro...
Are there alternatives to (2E,2'E)-3,3'-(1,4-Phenylene)bisacrylaldehyde in synthesis?
Alternatives to (2E,2'E)-3,3'-(1,4-Phenylene)bisacrylaldehyde include other acry...
What is 3-Amino-5-chloropyridin-2-ol hydrochloride (CAS: 1261906-29-9)?
3-Amino-5-chloropyridin-2-ol hydrochloride is an organic compound with the CAS n...
What precautions should be taken when handling 6,7-Difluoro-2,3-dihydro-4H-chromen-4-one (CAS: 1092349-93-3)?
When handling 6,7-Difluoro-2,3-dihydro-4H-chromen-4-one, it is essential to wear...
Source Journal
Journal of Materials Chemistry B

Journal of Materials Chemistry A, B & C cover high quality studies across all fields of materials chemistry. The journals focus on those theoretical or experimental studies that report new understanding, applications, properties and synthesis of materials. The journals have a strong history of publishing quality reports of interest to interdisciplinary communities and providing an efficient and rigorous service through peer review and publication. The journals are led by an international team of Editors-in-Chief and Associate Editors who are all active researchers in their fields. Journal of Materials Chemistry A, B & C are separated by the intended application of the material studied. Broadly, applications in energy and sustainability are of interest to Journal of Materials Chemistry A, applications in biology and medicine are of interest to Journal of Materials Chemistry B, and applications in optical, magnetic and electronic devices are of interest to Journal of Materials Chemistry C. More than one Journal of Materials Chemistry journal may be suitable for certain fields and researchers are encouraged to submit their paper to the journal that they feel best fits for their particular article. Example topic areas within the scope of Journal of Materials Chemistry B are listed below. This list is neither exhaustive nor exclusive. Antifouling coatings Biocompatible materials Bioelectronics Bioimaging Biomimetics Biomineralisation Bionics Biosensors Diagnostics Drug delivery Gene delivery Immunobiology Nanomedicine Regenerative medicine & Tissue engineering Scaffolds Soft robotics Stem cells Therapeutic devices image block All articles published in Journal of Materials Chemistry B from 2019 onwards will be indexed in MEDLINE®. Articles that primarily focus on providing insight into the underlying science and performance of biomaterials within a biological environment are more suited to our companion journal, Biomaterials Science.














