Online monitoring by infrared spectroscopy using multivariate analysis – background theory and application to catalytic dehydrogenative coupling of butanol to butyl butyrate

Literature Information

Publication Date 2019-02-11
DOI 10.1039/C8RE00238J
Impact Factor 4.239
Authors

Léo Violet, Alexis Mifleur, Laurent Vanoye, Duc Hanh Nguyen, Régis Philippe, Régis M. Gauvin, Pascal Fongarland


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Abstract

The monitoring of chemical reactions can be arduous especially when sampling is required with highly reactive compounds. Online spectroscopic methods provide efficient and non-invasive ways to record the composition of reactive mixtures, yet their use is often limited by the interpretation of spectroscopic data. Herein, we report an easy access and reproducible method for the online analysis of organic transformations through FTIR spectroscopy. Spectra are treated with a multivariate approach to lead to the accurate quantification of the chemicals involved. Further, the technique was applied to the acceptorless dehydrogenation coupling (ADC) of alcohol and allows the first in situ quantitative assessment of the aldehyde intermediate.

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Source Journal

Reaction Chemistry & Engineering

Reaction Chemistry & Engineering
CiteScore: 0
Self-citation Rate: 8.8%
Articles per Year: 284

Reaction Chemistry & Engineering is an interdisciplinary journal reporting cutting-edge research focused on enhancing the understanding and efficiency of reactions. Reaction engineering leverages the interface where fundamental molecular chemistry meets chemical engineering and technology. Challenges in chemistry can be overcome by the application of new technologies, while engineers may find improved solutions for process development from the latest developments in reaction chemistry. Reaction Chemistry & Engineering is a unique forum for researchers whose interests span the broad areas of chemical engineering and chemical sciences to come together in solving problems of importance to wider society. All papers should be written to be approachable by readers across the engineering and chemical sciences. Papers that consider multiple scales, from the laboratory up to and including plant scale, are particularly encouraged.

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