Synthesis of highly rigid phosphine–oxazoline ligands for palladium-catalyzed asymmetric allylic alkylation
Literature Information
Zhongxuan Qiu, Rui Sun, Dawei Teng
A highly rigid spiro phosphine–oxazoline ligand skeleton with a spirocarbon stereogenic center was developed from 7-bromo-1-indanone. The catalytic performance of the ligand was demonstrated in palladium-catalyzed asymmetric allylic alkylation. Under optimized conditions, high yields (up to 99%) and enantioselectivities (up to 99.9% ee) were obtained for reactions of 1,3-diphenylallyl acetates and symmetrical 1,3-dicarbonyl substrates.
Recommended Journals

Russian Journal of Coordination Chemistry

Russian Chemical Bulletin

Organic Process Research & Development

Current Opinion in Colloid & Interface Science

Journal of Saudi Chemical Society

Saudi Pharmaceutical Journal

Crystallography Reports

Chemistry Education Research and Practice

Journal of Peptide Science

Russian Journal of Bioorganic Chemistry
Related Literature
Synthesis of polyethers from epoxides via a binary organocatalyst system
Ge-Ge Gu, Li-Yang Wang, Rong Zhang, Tian-Jun Yue, Bai-Hao Ren, Wei-Min Ren
DOI: 10.1039/D1PY01085A
Thermoresponsive polymers as macromolecular coordination ligands: complexation-dependence of thermally induced aggregation in aqueous solution
Maximilian Felix Toni Meier, Franck Thetiot, Narsimhulu Pittala, Ingo Lieberwirth, Cleiton Kunzler, Smail Triki, Ulrich Jonas
DOI: 10.1039/D1PY00847A
Self-healing behaviour of furan–maleimide poly(ionic liquid) covalent adaptable networks
Katelyn M. Lindenmeyer, R. Daniel Johnson, Kevin M. Miller
DOI: 10.1039/D0PY00016G
Green-light photocleavable meso-methyl BODIPY building blocks for macromolecular chemistry
Paul Strasser, Pauline Stadler, Patrick Breiteneder, Günther Redhammer, Markus Himmelsbach, Oliver Brüggemann, Uwe Monkowius, Ian Teasdale
DOI: 10.1039/D1PY01245B
Porous polycaprolactone and polycarbonate poly(urethane urea)s via emulsion templating: structures, properties, cell growth‡
Katya Kapilov-Buchman, Tslil Bialystocki, Danna Niezni, Luba Perry, Shulamit Levenberg, Michael S. Silverstein
DOI: 10.1039/D1PY01106E
Aqueous copper-mediated reversible deactivation radical polymerization (RDRP) utilizing polyetheramine derived initiators‡
Jirui Zhang, Evelina Liarou, James Town, Yongguang Li, Alan M. Wemyss, David M. Haddleton
DOI: 10.1039/D0PY00555J
Balancing the transesterification reactivity of isosorbide with diphenyl carbonate: preferential activation of exo-OH
Ming Zhang, Yifei Tu, Zibo Zhou, Guozhang Wu
DOI: 10.1039/D0PY00764A
Designing self-propagating polymers with ultrasensitivity through feedback signal amplification
Jiajia Tan, Jinming Hu, Shiyong Liu
DOI: 10.1039/D1PY01095F
Tuning the thermoresponsive properties of PEG-based fluorinated polymers and stimuli responsive drug release for switchable 19F magnetic resonance imaging
Nyoman D. Kurniawan
DOI: 10.1039/D1PY00602A
You might also like
What is the market or research trend for N-(4-Methoxybenzyl)-2-pyridinamine (CAS: 52818-63-0)?
N-(4-Methoxybenzyl)-2-pyridinamine (CAS: 52818-63-0) is increasingly being used ...
What precautions should be taken when handling Ethyl 4-(2-chlorophenyl)-1,3-thiazole-2-carboxylate (CAS: 1050507-06-6)?
When handling Ethyl 4-(2-chlorophenyl)-1,3-thiazole-2-carboxylate, appropriate p...
What regulatory guidelines apply to diethyldiselane (CAS: 628-39-7)?
Diethyldiselane (CAS: 628-39-7) is classified under the Globally Harmonized Syst...
What is the market or research trend for oxocopper (CAS: 12053-18-8)?
The market for oxocopper (CAS: 12053-18-8) is primarily driven by its use in cat...
What is the market or research trend for 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.4]heptane-7-carboxylic acid?
The market for 5-{[(2-Methyl-2-propanyl)oxy]carbonyl}-5-azaspiro[2.4]heptane-7-c...
What is 2-(1-Pyrrolidinyl)-4-pyridinamine (CAS: 35981-63-6)?
2-(1-Pyrrolidinyl)-4-pyridinamine is a chemical compound with the CAS number 359...
What are the physical and chemical properties of 2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane (CAS: 91556-75-1)?
2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane (CAS: 91556-75-1) is a crystalline sol...
How is (S)-Alpha-allyl-proline hydrochloride (CAS: 129704-91-2) typically synthesized?
(S)-Alpha-allyl-proline hydrochloride is usually synthesized via a Wittig reacti...
What is 3-Methyl-1,2-oxazole-5-carboxylic acid (CAS: 4857-42-5)?
3-Methyl-1,2-oxazole-5-carboxylic acid (CAS: 4857-42-5) is an organic compound w...
How is Lys-SMCC-DM1 (CAS: 1281816-04-3) typically synthesized?
Lys-SMCC-DM1 is synthesized via a multi-step process involving the coupling of S...
Source Journal
Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.
![1-oxaspiro[4.4]nonan-6-one structure 1-oxaspiro[4.4]nonan-6-one structure](https://static.chemtradehub.com/structs/134/134179-01-4-e051.webp)



