A unique self-assembly-driven probe for sensing a lipid bilayer: ratiometric probing of vesicle to micelle transition

Literature Information

Publication Date 2018-05-02
DOI 10.1039/C8CC01635F
Impact Factor 6.222
Authors

Santanu Bhattacharya


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Abstract

An amphiphilic pyrene–terpyridine (Pytpy) probe forms novel, fluorescent nanoaggregates in phospholipid membranes. This unique membrane-driven self-assembly of Pytpy shows large Stokes shifts and long-lived fluorescent states and efficiently reports on vesicle–micelle transition through ratiometric changes. Strikingly, Pytpy can even distinguish between bilayer-like domains and more-dynamic micelle-like ‘rim’ phases that co-exist in mixed assemblies (bicelles).

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