Channel current analysis estimates the pore-formation and the penetration of transmembrane peptides
Literature Information
Publication Date
2018-05-02
DOI
10.1039/C8AN00243F
Impact Factor
4.616
Authors
Yusuke Sekiya, Shungo Sakashita, Keisuke Shimizu, Kenji Usui, Ryuji Kawano
View Original
Abstract
We measured the current signal of the transmembrane model peptides using the barrel-stave, toroidal pore, and penetration models in order to establish a precise assignment of the channel signals. In addition, we analyzed the spike signals to estimate the membrane penetration of model cell-penetration peptides of different lengths.
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